Overview


P2X7 receptor, an ATP-gated and non-selective cation channel that can regulate inflammatory disease has been implicated. The release of pro-inflammatory cytokines can be caused by the activation of the P2X7 channel by high levels of adenosine triphosphate (ATP). This has been linked to a wide range of diseases. There is currently no P2X7 antagonist on the market. Clinical trials have not yet begun to identify any P2X7 antagonists. P2X7R, a subtype of the seven purinergic P2X7 receptors that are ATP-gated, non-selective Cation Channels, is unique. There have been reports that P2X7R plays a pathological role in a variety of diseases, including arthritis, inflammatory bowel disease, neurodegenerative disorders, chronic pain, mood disorders, and cancers. Many pharmaceutical companies have attempted to develop a clinical candidate for P2X7R. P2X7 receptor, an ATP-gated and non-selective cation channel, is associated with a variety of inflammatory disorders. P2X7 receptor antagonists are therapeutic agents. Pain management is a common use of opioid medications.

P2X7R, a subtype of the seven purinergic P2X receptors (ATP-gated nonselective Cation Channels), is unique. The pathological role of P2X7R in various diseases has been documented, including neurodegenerative diseases and chronic pain, mood disorders, cancers, and arthritis. A P2X7 Receptor Antagonist, or RA, is a pain medication that blocks the brain's activity of the ligand. The P2X7 Receptor is an important molecule that initiates inflammatory processes within the body. The approval and launch of an alternative pain management option are expected to be a breakthrough in this space. P2X7 has been linked to major depression. Animal studies have also shown that P2X7 antagonists can cause P2X7 to act in a way similar to antidepressants. Inflammation, mood disorders, and depression are all possible areas where P2X7 may be involved. Its antagonism could also help to modify treatment. Numerous research studies have shown that P2X7 channels are activated by the pro-inflammatory cytokines IL-1b, and IL-18. Extracellular ATP has a low affinity for P2X7, compared to other purinergic ion channel channels (P2X4, P2X3, etc.). The therapeutic benefits of P2X7 receptor antagonists are significant, since P2X7 receptors are associated with inflammation regulation, and all immune cells (lymphocytes macrophages monocytes, and lymphocytes) express P2X7.

FutureWise Market Research has instantiated a report that provides an intricate analysis of P2X7 Receptor Antagonists Market trends that shall affect the overall market growth. Furthermore, it includes detailed information on the graph of profitability, SWOT analysis, market share and regional proliferation of this business. Moreover, the report offers insights on the current stature of prominent market players in the competitive landscape analysis of this market.

According to the research study conducted by FutureWise research analysts, the P2X7 Receptor Antagonists Market is anticipated to attain substantial growth by the end of the forecast period. The report explains that this business is predicted to register a noteworthy growth rate over the forecast period. This report provides crucial information pertaining to the total valuation that is presently held by this industry and it also lists the segmentation of the market along with the growth opportunities present across this business vertical.

  • GlaxoSmithKline Plc
  • Johnson and Johnson
  • AstraZeneca Plc
  • RaQualia Pharma
  • Evotec AG
  • Asahi Kasei Corporation
  • Pfizer

(Note: The list of the major players will be updated with the latest market scenario and trends)

By Drug Product

  • AKP-23494954/RQ-00466479
  • EVT 401
  • GSK1482160
  • JNJ-55308942
  • JNJ-54175446
  • Others

By Application

  • Central Nervous System Disorders
  • Immunological Disorders
  • Others

By End-User

  • Hospital
  • Ambulatory Surgical Center
  • Pharmaceutical and Botechnology Companies

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

  • Tier 1 players- established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants

  • Growth prospects
  • SWOT analysis
  • Key trends
  • Key data-points affecting market growth

  • To provide with an exhaustive analysis on the P2X7 Receptor Antagonists Market By Drug Product, By Application, By End-User and By Region.
  • To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
  • To evaluate and forecast micro-markets and the overall market
  • To predict the market size, in key regions— North America, Europe, Asia Pacific, Latin America and Middle East and Africa.
  • To record and evaluate competitive landscape mapping- product launches, technological advancements, mergers and expansions

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Table of Contents


  • 1.   Market Introduction
    •   1. Objectives of the Study
        2. Market Definition
        3. Market Scope
         3.1. Years Considered for the Study
         3.2. Market Covered
        4. Currency
        5. Limitations
        6. Stakeholders
  • 2.   Research Methodology
    •   1. Research Data
         1.1. Secondary Data
          1.1.1. Key Data from Secondary Sources
         1.2. Primary Data
          1.2.1. Key Data from Primary Sources
        2. Market Size Estimation
        3. Market Breakdown and Data Triangulation
        4. Assumptions for the Study
  • 3.   Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights
  • 4.   P2X7 Receptor Antagonists Market Variables, Trends and Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Technology Overview
        6. Regulatory Framework
         6.1. Reimbursement Framework
         6.2. Standards and Compliances

  • 5.   Market Overview
    •   1. Market Dynamics
         1.1. Market Driver Analysis
          1.1.1. Increasing focus of P2X7 Receptor Antagonists Market Companies on Brand Protection
          1.1.2. Untapped Opportunities in Emerging Regions
         1.2. Market Restraint Analysis
          1.2.1. High Cost Associated with Implementation of Predictive Analysis
         1.3. Industry Challenges
          1.3.1. Presence of Ambiguous Regulatory Framework
  • 6.   P2X7 Receptor Antagonists Market Analysis Tools
    •   1. Industry Analysis - Porter’s
         1.1. Supplier Power
         1.2. Buyer Power
         1.3. Substitution Threat
         1.4. Threat from New Entrants
         1.5. Competitive Rivalry
        2. Pestel Analysis
         2.1. Political Landscape
         2.2. Environmental Landscape
         2.3. Social Landscape
         2.4. Technology Landscape
         2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
         3.1. Joint Ventures
         3.2. Mergers and Acquisitions
         3.3. Licensing and Partnership
         3.4. Technology Collaborations
         3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies
  • 7.   P2X7 Receptor Antagonists Market, By Drug Product Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. AKP-23494954/RQ-00466479
        2. EVT 401
        3. GSK1482160
        4. JNJ-55308942
        5. JNJ-54175446
        6. Others

  • 8.   P2X7 Receptor Antagonists Market, By Application Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Central Nervous System Disorders
        2. Immunological Disorders
        3. Others

  • 9.   P2X7 Receptor Antagonists Market, By End-User Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Hospital
        2. Ambulatory Surgical Center
        3. Pharmaceutical and Botechnology Companies

  • 10.   North America P2X7 Receptor Antagonists Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. U.S.A
         2.2. Canada
         2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2023-2031

  • 11.   Latin America P2X7 Receptor Antagonists Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Brazil
         2.2. Venezuela
         2.3. Argentina
         2.4. Rest of Latin America
        3. Market Size (USD Million) Forecast for Latin America 2023-2031

  • 12.   Europe P2X7 Receptor Antagonists Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Germany
         2.2. U.K
         2.3. France
         2.4. Italy
         2.5. Spain
         2.6. Russia
         2.7. Poland
         2.8. Rest of Europe
        3. Market Size (USD Million) Forecast for Europe 2023-2031

  • 13.   Asia Pacific P2X7 Receptor Antagonists Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Japan
         2.2. China
         2.3. India
         2.4. Australia and New Zealand
         2.5. ASEAN
         2.6. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2023-2031

  • 14.   Middle East and Africa Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. GCC
         2.2. Israel
         2.3. South Africa
         2.4. Rest of MEA
        3. Market Size (USD Million) Forecast for MEA 2023-2031

  • 15.   Market Share Analysis and Competitive Landscape
    •   1. Global Landscape - Key Players, Revenue and Presence
        2. Global Share Analysis - Key Players (Tier 1, Tier 2, Tier 3)
        3. Global Emerging Companies
        4. North America - Market Share Analysis and Key Regional Players
        5. Europe - Market Share Analysis and Key Regional Players
        6. Asia Pacific - Market Share Analysis and Key Regional Players
        7. Global Key Player - Growth Matrix
  • 16.   Company Profiles (Competition Dashboard, Competitors Deep Dive, Products Offered and Financial Layouts)
    •   1. GlaxoSmithKline Plc
         1.1. Company Overview
         1.2. Product Portfolio
         1.3. SWOT Analysis
         1.4. Financial Overview
         1.5. Strategic Overview
        2. Johnson and Johnson
         2.1. Company Overview
         2.2. Product Portfolio
         2.3. SWOT Analysis
         2.4. Financial Overview
         2.5. Strategic Overview
        3. AstraZeneca Plc
         3.1. Company Overview
         3.2. Product Portfolio
         3.3. SWOT Analysis
         3.4. Financial Overview
         3.5. Strategic Overview
        4. RaQualia Pharma
         4.1. Company Overview
         4.2. Product Portfolio
         4.3. SWOT Analysis
         4.4. Financial Overview
         4.5. Strategic Overview
        5. Evotec AG
         5.1. Company Overview
         5.2. Product Portfolio
         5.3. SWOT Analysis
         5.4. Financial Overview
         5.5. Strategic Overview
        6. Asahi Kasei Corporation
         6.1. Company Overview
         6.2. Product Portfolio
         6.3. SWOT Analysis
         6.4. Financial Overview
         6.5. Strategic Overview
        7. Pfizer
         7.1. Company Overview
         7.2. Product Portfolio
         7.3. SWOT Analysis
         7.4. Financial Overview
         7.5. Strategic Overview

  • 17.   Pre and Post COVID-19 Impact
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the regulations initiated by healthcare administrations
        5. The overall economic slowdown of the developing and developed nations
  • 18.   FutureWise SME Key Takeaway Points for Client
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