Overview


According to FutureWise analysis the market for methymalonic acidemia in 2023 is US$ 9.64 billion, and is expected to reach US$ 14.48 billion by 2031 at a CAGR of 5.22%.

Metabolic disorders such as methylmalonic acidemia cause the body to have problems breaking down certain proteins and fats. A substance called methylmalonic acid builds up in the blood as a result. The condition is passed down through families. One of several conditions called an "inborn error of metabolism." Symptoms may include lethargy, failure to thrive, recurrent vomiting, acidosis, dehydration, respiratory distress, diminished muscle tone, developmental retardation, seizures, and/or an enlarged liver. In methylmalonic acidemia, the body cannot properly process certain proteins and fats (lipids). Early infancy is usually when methylmalonic acidemia appears and its effects can range from mild to life-threatening. It can cause vomiting, dehydration, weak muscle tone (hypotonia), developmental delay, excessive tiredness (lethargy), and failure to gain weight and grow at the expected rate (failure to thrive). Complications can include feeding difficulties, intellectual disability, chronic kidney disease, and pancreatitis (inflammation of the pancreas). There are some cases in which this disorder can lead to coma or death without treatment. MMA (methylmalonic acidemia) is a type of heterogeneous disorder caused by gene mutations, where the body cannot break down certain proteins and fats, causing methylmalonic acid to build up in the blood or urine. There are genetic defects related to the metabolism of methyl malonyl-coenzyme A (CoA), vitamin B12, or any dietary deficiency that is passed from one generation to the next. Other biochemical abnormalities associated with MMA include low methionine and elevated homocysteine, and children with MMA lack the protein required by their bodies to digest food. Defining methylmalonic acidemia as the inability of the body to breakdown certain proteins and fats, it is a metabolic disorder. The result is a buildup of methylmalonic acid in the blood, which is passed down from generation to generation. In methylmalonic acidemia (MMA), the body is unable to properly break down certain proteins and fats (lipids) because of an inherited condition. Early infancy is usually the time when the disease appears, ranging from mild to life-threatening. It is caused by mutations in the genes MMUT, MMAA, MMAB, MMADHC, and MCEE.

FutureWise Market Research has instantiated a report that provides an intricate analysis of Methymalonic Acidemia Market trends that shall affect the overall market growth. Furthermore, it includes detailed information on the graph of profitability, SWOT analysis, market share and regional proliferation of this business. Moreover, the report offers insights on the current stature of prominent market players in the competitive landscape analysis of this market.

According to the research study conducted by FutureWise research analysts, the Methymalonic Acidemia Market is anticipated to attain substantial growth by the end of the forecast period. The report explains that this business is predicted to register a noteworthy growth rate over the forecast period. This report provides crucial information pertaining to the total valuation that is presently held by this industry and it also lists the segmentation of the market along with the growth opportunities present across this business vertical.

  • Lonza Group Ltd
  • DSM
  • Ceva Sante Animale S.A.
  • Biosint S.p.A.
  • Cayman Chemical
  • Tokyo Chemical Industry Co., Ltd.
  • Chengda Pharmaceuticals Co. Ltd
  • Sanofi
  • Johnlee Pharmaceuticals Pvt. Ltd
  • Merck KGaA

(Note: The list of the major players will be updated with the latest market scenario and trends)

By Disorder Type

  • Homocystinuria
  • Isolated Methylmalonic Acidurias
  • Combined Methylmalonic Aciduria

By Indication

  • Acidosis
  • Ketosis
  • Hyperammonemia
  • Hypoglycemia
  • Hyperglycemia
  • Neutropenia
  • Other Indications

By Distribution Channel

  • Hospitals
  • Pharmacies
  • Clinics
  • Others

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

  • Tier 1 players- established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants

  • Growth prospects
  • SWOT analysis
  • Key trends
  • Key data-points affecting market growth

  • To provide with an exhaustive analysis on the Methymalonic Acidemia Market By Disorder Type, By Indication, By Distribution Channel and By Region.
  • To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
  • To evaluate and forecast micro-markets and the overall market
  • To predict the market size, in key regions— North America, Europe, Asia Pacific, Latin America and Middle East and Africa.
  • To record and evaluate competitive landscape mapping- product launches, technological advancements, mergers and expansions

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Table of Contents


  • 1.   Market Introduction
    •   1. Objectives of the Study
        2. Market Definition
        3. Market Scope
         3.1. Years Considered for the Study
         3.2. Market Covered
        4. Currency
        5. Limitations
        6. Stakeholders
  • 2.   Research Methodology
    •   1. Research Data
         1.1. Secondary Data
          1.1.1. Key Data from Secondary Sources
         1.2. Primary Data
          1.2.1. Key Data from Primary Sources
        2. Market Size Estimation
        3. Market Breakdown and Data Triangulation
        4. Assumptions for the Study
  • 3.   Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights
  • 4.   Methymalonic Acidemia Market Variables, Trends and Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Technology Overview
        6. Regulatory Framework
         6.1. Reimbursement Framework
         6.2. Standards and Compliances

  • 5.   Market Overview
    •   1. Market Dynamics
         1.1. Market Driver Analysis
          1.1.1. Increasing focus of Methymalonic Acidemia Market Companies on Brand Protection
          1.1.2. Untapped Opportunities in Emerging Regions
         1.2. Market Restraint Analysis
          1.2.1. High Cost Associated with Implementation of Predictive Analysis
         1.3. Industry Challenges
          1.3.1. Presence of Ambiguous Regulatory Framework
  • 6.   Methymalonic Acidemia Market Analysis Tools
    •   1. Industry Analysis - Porter’s
         1.1. Supplier Power
         1.2. Buyer Power
         1.3. Substitution Threat
         1.4. Threat from New Entrants
         1.5. Competitive Rivalry
        2. Pestel Analysis
         2.1. Political Landscape
         2.2. Environmental Landscape
         2.3. Social Landscape
         2.4. Technology Landscape
         2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
         3.1. Joint Ventures
         3.2. Mergers and Acquisitions
         3.3. Licensing and Partnership
         3.4. Technology Collaborations
         3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies
  • 7.   Methymalonic Acidemia Market, By Disorder Type Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Homocystinuria
        2. Isolated Methylmalonic Acidurias
        3. Combined Methylmalonic Aciduria

  • 8.   Methymalonic Acidemia Market, By Indiaction Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Acidosis
        2. Ketosis
        3. Hyperammonemia
        4. Hypoglycemia
        5. Hyperglycemia
        6. Neutropenia
        7. Other Indications

  • 9.   Methymalonic Acidemia Market, By Distribution Channel Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Hospitals
        2. Pharmacies
        3. Clinics
        4. Others

  • 10.   North America Methymalonic Acidemia Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. U.S.A
         2.2. Canada
         2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2023-2031

  • 11.   Latin America Methymalonic Acidemia Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Brazil
         2.2. Venezuela
         2.3. Argentina
         2.4. Rest of Latin America
        3. Market Size (USD Million) Forecast for Latin America 2023-2031

  • 12.   Europe Methymalonic Acidemia Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Germany
         2.2. U.K
         2.3. France
         2.4. Italy
         2.5. Spain
         2.6. Russia
         2.7. Poland
         2.8. Rest of Europe
        3. Market Size (USD Million) Forecast for Europe 2023-2031

  • 13.   Asia Pacific Methymalonic Acidemia Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Japan
         2.2. China
         2.3. India
         2.4. Australia and New Zealand
         2.5. ASEAN
         2.6. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2023-2031

  • 14.   Middle East and Africa Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. GCC
         2.2. Israel
         2.3. South Africa
         2.4. Rest of MEA
        3. Market Size (USD Million) Forecast for MEA 2023-2031

  • 15.   Market Share Analysis and Competitive Landscape
    •   1. Global Landscape - Key Players, Revenue and Presence
        2. Global Share Analysis - Key Players (Tier 1, Tier 2, Tier 3)
        3. Global Emerging Companies
        4. North America - Market Share Analysis and Key Regional Players
        5. Europe - Market Share Analysis and Key Regional Players
        6. Asia Pacific - Market Share Analysis and Key Regional Players
        7. Global Key Player - Growth Matrix
  • 16.   Company Profiles (Competition Dashboard, Competitors Deep Dive, Products Offered and Financial Layouts)
    •   1. Lonza Group Ltd
         1.1. Company Overview
         1.2. Product Portfolio
         1.3. SWOT Analysis
         1.4. Financial Overview
         1.5. Strategic Overview
        2. DSM
         2.1. Company Overview
         2.2. Product Portfolio
         2.3. SWOT Analysis
         2.4. Financial Overview
         2.5. Strategic Overview
        3. Ceva Sante Animale S.A.
         3.1. Company Overview
         3.2. Product Portfolio
         3.3. SWOT Analysis
         3.4. Financial Overview
         3.5. Strategic Overview
        4. Biosint S.p.A.
         4.1. Company Overview
         4.2. Product Portfolio
         4.3. SWOT Analysis
         4.4. Financial Overview
         4.5. Strategic Overview
        5. Cayman Chemical
         5.1. Company Overview
         5.2. Product Portfolio
         5.3. SWOT Analysis
         5.4. Financial Overview
         5.5. Strategic Overview
        6. Tokyo Chemical Industry Co., Ltd.
         6.1. Company Overview
         6.2. Product Portfolio
         6.3. SWOT Analysis
         6.4. Financial Overview
         6.5. Strategic Overview
        7. Chengda Pharmaceuticals Co. Ltd
         7.1. Company Overview
         7.2. Product Portfolio
         7.3. SWOT Analysis
         7.4. Financial Overview
         7.5. Strategic Overview
        8. Sanofi
         8.1. Company Overview
         8.2. Product Portfolio
         8.3. SWOT Analysis
         8.4. Financial Overview
         8.5. Strategic Overview
        9. Johnlee Pharmaceuticals Pvt. Ltd
         9.1. Company Overview
         9.2. Product Portfolio
         9.3. SWOT Analysis
         9.4. Financial Overview
         9.5. Strategic Overview
        10. Merck KGaA
         10.1. Company Overview
         10.2. Product Portfolio
         10.3. SWOT Analysis
         10.4. Financial Overview
         10.5. Strategic Overview

  • 17.   Pre and Post COVID-19 Impact
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the regulations initiated by healthcare
                  administrations
        5. The overall economic slowdown of the developing and developed nations

  • 18.   FutureWise SME Key Takeaway Points for Client
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