Overview


According to FutureWise analysis the market for immune repertoire sequencing is expected to reach US$ 0.29 billion by 2031 at a CAGR of 7.17%.

The immune repertoire is defined as the sum of T cell receptors and B cell receptors (also known as immunoglobulin) that comprise the adaptive immune system of an organism. B-cell receptor (BCR) and T-cell receptor (TCR) receptors on the surface of B and T cells, respectively, mediate human adaptive immune system protection. Next-generation sequencing (NGS) advancements have enabled the development of immune repertoire sequencing, a powerful new technology for probing the complementary determining region of these receptors. Immune repertoire sequencing has aided in the profiling of antigen-specific information within lymphocytes and has grown in importance in understanding the body's auto-defence mechanisms against foreign agents.

Animals that reproduce and are more suited to their environments are favoured by natural selection. During an immune response, only lymphocytes that have the proper receptor to bind to an antigen in the immune repertoire will be activated and multiply, creating a clone of cells with identical antigen receptors. Understanding the immune repertoire is essential in the development of targeted therapy and immunotherapy, where treatments are being developed that are customised to an individual for improved success. Many medications that affect the immune system are either being researched or are already in use. Assessing the immune repertoire may help with therapy result prediction and side effect monitoring. The use of cytokines as medicines is one example of a treatment that broadens the immune repertoire.

FutureWise Market Research has published a report that provides an insightful analysis of immune repertoire sequencing market trends that are affecting the overall market growth. This report will provide a detailed analysis of market share, regional insights, and competitor analysis that includes stature of key manufacturers operational in this industry. According to the analysis conducted by FutureWise research analysts, the immune repertoire sequencing market is estimated to register a considerable growth rate over the forecast period. This report lists the market segments and potential prospects available across this industry, in addition providing crucial information on the total valuation currently held by the industry. Moreover, this report will assist key management individuals in an organisation to enhance their decisions pertaining to business expansion as well as strategic changes for increasing customer base.

The key factor driving the worldwide immune repertoire sequencing market is the rise in government funding for various pharmacogenomics-based drug recovery techniques. Furthermore, the global market for immune repertoire sequencing is being driven ahead by the quick expansion of numerous therapeutic fields like infectious illnesses, cardiology, oncology, and pain management. Immune repertoire sequencing method development will become more important in the upcoming years if it can produce more specific sample information than existing techniques. Single-cell techniques are anticipated to drive the immune repertoire sequencing market throughout the forecast period due to their capacity to give high-dimensional and detailed information on smaller populations of interest, such as antigen-binding cells. Moreover, issues with immune repertoire sequencing technologies and variations in data collecting and processing among laboratories are some of the main factors that could restrict immunological development. The market's expansion is also anticipated to be hampered by a shortage of skilled staff to carry out immunological repertoire sequencing techniques established in specialised laboratories.

  • ABVITRO (NOW JUNO THERAPEUTICS)
  • ADAPTIVE BIOTECHNOLOGIES
  • AGILENT TECHNOLOGIES
  • ARCHERDX, INC
  • BGI
  • ILLUMINA, INC.
  • IREPERTOIRE, INC.
  • OXFORD NANOPORE TECHNOLOGIES, LTD
  • PACIFIC BIOSCIENCES
  • Qiagen N.V.
  • Takara Bio Inc.
  • CD Genomics
  • Roche Holding AG 
  • Thermo Fisher Scientific

(Note: The list of the major players will be updated with the latest market scenario and trends)

By Product

  • Instrument
    • NGS
    • PCR
  • Assay, Kits And Reagent
    • TCR Kits
      • Human TCR Kits
      • Mouse TCR Kits
    • BCR Kits
      • Human BCR Kits
      • Mouse BCR Kits
  • Analytical Software
    • TCR Analysis Solutions
    • BCR Analysis Solutions
    • TCR And BCR Analysis Solutions
  • Services
    • Pre-Sequencing Services
    • Sequencing Services
    • Data Analysis Services

By Application

  • Biomarker Discovery
  • Autoimmune Diseases
  • Cancer Immunotherapy
  • Infectious Disease Research
  • Asthma and Allergy Research
  • Vaccine Development
  • Immunodeficiency Identification
  • Others (If Any)

By End User

  • Diagnostic Labs
  • Pharmaceutical and Biotech Companies
  • Research Institutes
  • Others (If Any)

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

This market research report also emphasis on factors affecting the growth rate in various regions listed above. A deep-down analysis of region will also be provided in the final version of this market which is based on conclusion of primary interviews and secondary data point gathered during the process.

By region, the market is segmented into North America, Latin America, Europe, Asia-Pacific, and Middle East & Africa. North America registered highest share in the market in 2022. The Centres for Medicare & Medicaid Services (CMS) report that U.S. health spending increased to USD 4.1 trillion (or USD 12,530 per person) in 2020, up 9.7% from 2019. Also, the rising prevalence of autoimmune illnesses in the area is anticipated to fuel market expansion. For instance, about 10 million Americans, or about 3% of the population, are afflicted by autoimmune disorders. It is also anticipated that the presence of the largest pharmaceutical corporations in the world in the region will accelerate market expansion. Also, Adaptive technology is a player with highest market share in this target market.


  • Tier 1 players- established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants

  • Growth prospects
  • SWOT analysis
  • Key trends
  • Key data points affecting market growth

  • To provide with an exhaustive analysis on the Immune Repertoire Sequencing Market By Product, By Application, By End-User and By Region.
  • To cater comprehensive insights on factors such as drivers, restraints, trends, opportunity, and additionally segmental and regional factors impacting market growth.
  • To evaluate current market trends and forecast micro-markets and the overall market projections which are represented in the format of data-sets and ppt.
  • To predict the market size, in key regions— North America, Europe, Asia Pacific, Latin America and Middle East and Africa.
  • To provide information on competitors which includes landscape mapping, technological advancements, R&D spending, news concerning strategic alliances, and new product launches.

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Table of Contents


  • 1.   Market Introduction
    •   1. Objectives of the Study
        2. Market Definition
        3. Market Scope
         3.1. Years Considered for the Study
         3.2. Market Covered
        4. Currency
        5. Limitations
        6. Stakeholders
  • 2.   Research Methodology
    •   1. Research Data
         1.1. Secondary Data
          1.1.1. Key Data from Secondary Sources
         1.2. Primary Data
          1.2.1. Key Data from Primary Sources
        2. Market Size Estimation
        3. Market Breakdown and Data Triangulation
        4. Assumptions for the Study
  • 3.   Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights
  • 4.   Immune Repertoire Sequencing Market Variables, Trends and Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Technology Overview
        6. Regulatory Framework
         6.1. Reimbursement Framework
         6.2. Standards and Compliances

  • 5.   Market Overview
    •   1. Market Dynamics
         1.1. Market Driver Analysis
          1.1.1. Increasing focus of Immune Repertoire Sequencing Market Companies on Brand Protection
          1.1.2. Untapped Opportunities in Emerging Regions
         1.2. Market Restraint Analysis
          1.2.1. High Cost Associated with Implementation of Predictive Analysis
         1.3. Industry Challenges
          1.3.1. Presence of Ambiguous Regulatory Framework
  • 6.   Immune Repertoire Sequencing Market Analysis Tools
    •   1. Industry Analysis - Porter’s
         1.1. Supplier Power
         1.2. Buyer Power
         1.3. Substitution Threat
         1.4. Threat from New Entrants
         1.5. Competitive Rivalry
        2. Pestel Analysis
         2.1. Political Landscape
         2.2. Environmental Landscape
         2.3. Social Landscape
         2.4. Technology Landscape
         2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
         3.1. Joint Ventures
         3.2. Mergers and Acquisitions
         3.3. Licensing and Partnership
         3.4. Technology Collaborations
         3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies
  • 7.   Immune Repertoire Sequencing Market, By Product Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Instrument
         1.1. NGS
         1.2. PCR
        2. Assay, Kits and Reagent
         2.1. TCR Kits
          2.1.1. Human TCR Kits
          2.1.2. Mouse TCR Kits
         2.2. BCR Kits
          2.2.1. Human BCR Kits
          2.2.2. Mouse BCR Kits
        3. Analytical Software
         3.1. TCR Analysis Solutions
         3.2. BCR Analysis Solutions
         3.3. TCR And BCR Analysis Solutions
        4. Services
         4.1. Pre-Sequencing Services
         4.2. Sequencing Services
         4.3. Data Analysis Services

  • 8.   Immune Repertoire Sequencing Market, By Application Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Biomarker Discovery
        2. Autoimmune Diseases
        3. Cancer Immunotherapy
        4. Infectious Disease Research
        5. Asthma and Allergy Research
        6. Vaccine Development
        7. Immunodeficiency Identification
        8. Others (If Any)

  • 9.   Immune Repertoire Sequencing Market, By End User Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Diagnostic Labs
        2. Pharmaceutical and Biotech Companies
        3. Research Institutes
        4. Others (If Any)

  • 10.   North America Immune Repertoire Sequencing Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. U.S.A
         2.2. Canada
         2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2023-2031

  • 11.   Latin America Immune Repertoire Sequencing Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Brazil
         2.2. Venezuela
         2.3. Argentina
         2.4. Rest of Latin America
        3. Market Size (USD Million) Forecast for Latin America 2023-2031

  • 12.   Europe Immune Repertoire Sequencing Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Germany
         2.2. U.K
         2.3. France
         2.4. Italy
         2.5. Spain
         2.6. Russia
         2.7. Poland
         2.8. Rest of Europe
        3. Market Size (USD Million) Forecast for Europe 2023-2031

  • 13.   Asia Pacific Immune Repertoire Sequencing Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Japan
         2.2. China
         2.3. India
         2.4. Australia and New Zealand
         2.5. ASEAN
         2.6. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2023-2031

  • 14.   Middle East and Africa Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. GCC
         2.2. Israel
         2.3. South Africa
         2.4. Rest of MEA
        3. Market Size (USD Million) Forecast for MEA 2023-2031

  • 15.   Market Share Analysis and Competitive Landscape
    •   1. Global Landscape - Key Players, Revenue and Presence
        2. Global Share Analysis - Key Players (Tier 1, Tier 2, Tier 3)
        3. Global Emerging Companies
        4. North America - Market Share Analysis and Key Regional Players
        5. Europe - Market Share Analysis and Key Regional Players
        6. Asia Pacific - Market Share Analysis and Key Regional Players
        7. Global Key Player - Growth Matrix
  • 16.   Company Profiles (Competition Dashboard, Competitors Deep Dive, Products Offered and Financial Layouts)
    •   1. ABVITRO (NOW JUNO THERAPEUTICS)
         1.1. Company Overview
         1.2. Product Portfolio
         1.3. SWOT Analysis
         1.4. Financial Overview
         1.5. Strategic Overview
        2. ADAPTIVE BIOTECHNOLOGIES
         2.1. Company Overview
         2.2. Product Portfolio
         2.3. SWOT Analysis
         2.4. Financial Overview
         2.5. Strategic Overview
        3. AGILENT TECHNOLOGIES
         3.1. Company Overview
         3.2. Product Portfolio
         3.3. SWOT Analysis
         3.4. Financial Overview
         3.5. Strategic Overview
        4. ARCHERDX, INC.
         4.1. Company Overview
         4.2. Product Portfolio
         4.3. SWOT Analysis
         4.4. Financial Overview
         4.5. Strategic Overview
        5. BGI
         5.1. Company Overview
         5.2. Product Portfolio
         5.3. SWOT Analysis
         5.4. Financial Overview
         5.5. Strategic Overview
        6. ILLUMINA, INC.
         6.1. Company Overview
         6.2. Product Portfolio
         6.3. SWOT Analysis
         6.4. Financial Overview
         6.5. Strategic Overview
        7. IREPERTOIRE, INC.
         7.1. Company Overview
         7.2. Product Portfolio
         7.3. SWOT Analysis
         7.4. Financial Overview
         7.5. Strategic Overview
        8. OXFORD NANOPORE TECHNOLOGIES, LTD
         8.1. Company Overview
         8.2. Product Portfolio
         8.3. SWOT Analysis
         8.4. Financial Overview
         8.5. Strategic Overview
        9. PACIFIC BIOSCIENCES
         9.1. Company Overview
         9.2. Product Portfolio
         9.3. SWOT Analysis
         9.4. Financial Overview
         9.5. Strategic Overview
        10. Qiagen N.V.
         10.1. Company Overview
         10.2. Product Portfolio
         10.3. SWOT Analysis
         10.4. Financial Overview
         10.5. Strategic Overview
        11. Takara Bio Inc.
         11.1. Company Overview
         11.2. Product Portfolio
         11.3. SWOT Analysis
         11.4. Financial Overview
         11.5. Strategic Overview
        12. CD Genomics
         12.1. Company Overview
         12.2. Product Portfolio
         12.3. SWOT Analysis
         12.4. Financial Overview
         12.5. Strategic Overview
        13. Roche Holding AG
         13.1. Company Overview
         13.2. Product Portfolio
         13.3. SWOT Analysis
         13.4. Financial Overview
         13.5. Strategic Overview
        14. Thermo Fisher Scientific
                 14.1. Company Overview
         14.2. Product Portfolio
         14.3. SWOT Analysis
         14.4. Financial Overview
         14.5. Strategic Overview

  • 17.   Pre and Post COVID-19 Impact
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the regulations initiated by healthcare administrations
        5. The overall economic slowdown of the developing and developed nations
  • 18.   FutureWise SME Key Takeaway Points for Client

FAQ


Immune Repertoire Sequencing is pivotal in research areas such as vaccine development, cancer immunotherapy, autoimmunity studies, and infectious disease monitoring. In diagnostics, it is used to assess lymphoid malignancies, track patient responses to immunotherapies, and identify potential biomarkers for various diseases.

While general sequencing methods capture the broad genomic information, IR-seq specifically targets the unique regions of the immune cells’ receptors. This focus allows for a deeper understanding of the immune system's capacity to recognize and fight off diverse pathogens and diseased cells.

The scope of this market is vast and growing, owing to increasing applications in personalized medicine. Though market sizes vary by analysis, there is a trend of substantial growth impacting healthcare through improved diagnostics and treatments with direct benefits for patient outcome and care.

Yes, our market forecast provides not only future projections but also historical data that gives context to the growth and evolution of the Immune Repertoire Sequencing Market. This data typically includes information on sales, therapeutic advancements, and market share distribution among key players.

Some of the latest trends include:
High-Throughput Sequencing: Rapid advances in technology allow processing of large sample volumes with deeper insights.
AI Integration: Artificial intelligence is being harnessed to interpret complex data.
Multiplexing Solutions: Platforms are being developed that can assess multiple immune parameters simultaneously.

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