Overview


According to FutureWise analysis the market for downstream processing in 2023 is US$ 27.35 billion, and is expected to reach US$ 65.34 billion by 2031 at a CAGR of 11.5%.

Purification and recovery of biosynthetic products, particularly medicines, from natural sources such as animal or plant tissues or fermentation broth is referred to as downstream processing. Downstream processing also includes the proper treatment and disposal of trash, as well as the recycling of salvageable components. Antibiotics, antibodies, hormones like insulin, vaccinations, and industrial enzymes are all manufactured using downstream processing. The downstream processing procedure is divided into five stages: solid-liquid separation, intracellular product release, concentration, purification using chromatography, and formulation. The proliferation of infectious diseases such as hepatitis, dengue fever, and swine flu is fuelling the growth of the downstream processing industry, as there is a high demand for effective vaccinations for such deadly diseases. The biotechnology industry relies heavily on downstream processing to extract and purify biological products. As a result, the isolation of biological products has aided the pharmaceutical industry's overall progress. Sales of biotechnology products have also increased significantly, contributing to the market's expansion. The development of innovative ways for bioprocessing antibodies has aided the market's expansion. For example, in June 2018, Novasep released a downstream processing tool for monoclonal antibodies, recombinant proteins, and blood factors that combines batch and continuous chromatography. The biotechnology industry has recently experienced unprecedented expansion, which has pushed the worldwide downstream processing market to new heights.

FutureWise Market Research has instantiated a report that provides an intricate analysis of Downstream Processing Market trends that shall affect the overall market growth. Furthermore, it includes detailed information on the graph of profitability, SWOT analysis, market share and regional proliferation of this business. Moreover, the report offers insights on the current stature of prominent market players in the competitive landscape analysis of this market.

According to the research study conducted by FutureWise research analysts, the Downstream Processing Market is anticipated to attain substantial growth by the end of the forecast period. The report explains that this business is predicted to register a noteworthy growth rate over the forecast period. This report provides crucial information pertaining to the total valuation that is presently held by this industry and it also lists the segmentation of the market along with the growth opportunities present across this business vertical.

  • Thermo Fisher Scientific Inc.
  • GE Healthcare
  • Sartorius Stedim Biotech S.A.
  • Merck Millipore
  • Danaher Corporation
  • Repligen
  • 3M Company
  • Boehringer Ingelheim International GmbH
  • Corning Corporation
  • Lonza Group Ltd
  • Dover Corporation
  • Ashai Kasei
  • Ferner PLC
  • Eppendorf A

(Note: The list of the major players will be updated with the latest market scenario and trends)

By Technique

  • Purification
  • Solid-liquid Separation
  • Clarification/Concentration

By Product

  • Chromatography Columns and Resins
  • Filters
  • Membrane Adsorbers
  • Single-use Products
  • Other Products (Consumables and Accessories)

By Application

  • Monoclonal Antibody Production
  • Vaccine Production
  • Insulin Production
  • Immunoglobulin Production
  • Erythropoietin Production
  • Other Applications (Interferons, Fusion Proteins, Growth Hormones, Blood Coagulation Factors, Anticoagulants, Medical Enzymes, Anti-bacterial (Antibiotics), and Colony Stimulating Factors)

By End User

  • Biopharmaceutical Manufacturers
  • Contract Manufacturing Organizations (CMOs)

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

  • Tier 1 players- established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants

  • Growth prospects
  • SWOT analysis
  • Key trends
  • Key data-points affecting market growth

  • To provide with an exhaustive analysis on the Downstream Processing Market By Technique, By Product, By Application, By End User and By Region.
  • To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
  • To evaluate and forecast micro-markets and the overall market
  • To predict the market size, in key regions— North America, Europe, Asia Pacific, Latin America and Middle East and Africa.
  • To record and evaluate competitive landscape mapping- product launches, technological advancements, mergers and expansions

  • We have a flexible delivery model and you can suggest changes in the scope/table of content as per your requirement
  • The customization Mobility Care offered are free of charge with purchase of any license of the report
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Table of Contents


  • 1.   Market Introduction
    •   1. Objectives of the Study
        2. Market Definition
        3. Market Scope
         3.1. Years Considered for the Study
         3.2. Market Covered
        4. Currency
        5. Limitations
        6. Stakeholders
  • 2.   Research Methodology
    •   1. Research Data
         1.1. Secondary Data
          1.1.1. Key Data from Secondary Sources
         1.2. Primary Data
          1.2.1. Key Data from Primary Sources
        2. Market Size Estimation
        3. Market Breakdown and Data Triangulation
        4. Assumptions for the Study
  • 3.   Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights
  • 4.   Downstream Processing Market Variables, Trends and Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Technology Overview
        6. Regulatory Framework
         6.1. Reimbursement Framework
         6.2. Standards and Compliances

  • 5.   Market Overview
    •   1. Market Dynamics
         1.1. Market Driver Analysis
          1.1.1. Increasing focus of Downstream Processing Market Companies on Brand Protection
          1.1.2. Untapped Opportunities in Emerging Regions
         1.2. Market Restraint Analysis
          1.2.1. High Cost Associated with Implementation of Predictive Analysis
         1.3. Industry Challenges
          1.3.1. Presence of Ambiguous Regulatory Framework
  • 6.   Downstream Processing Market Analysis Tools
    •   1. Industry Analysis - Porter’s
         1.1. Supplier Power
         1.2. Buyer Power
         1.3. Substitution Threat
         1.4. Threat from New Entrants
         1.5. Competitive Rivalry
        2. Pestel Analysis
         2.1. Political Landscape
         2.2. Environmental Landscape
         2.3. Social Landscape
         2.4. Technology Landscape
         2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
         3.1. Joint Ventures
         3.2. Mergers and Acquisitions
         3.3. Licensing and Partnership
         3.4. Technology Collaborations
         3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies
  • 7.   Downstream Processing Market, By Technique Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Purification
        2. Solid-liquid Separation
        3. Clarification/Concentration

  • 8.   Downstream Processing Market, By Product Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Chromatography Columns and Resins
        2. Filters
        3. Membrane Adsorbers
        4. Single-use Products
        5. Other Products (Consumables and Accessories)

  • 9.   Downstream Processing Market, By Application Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Monoclonal Antibody Production
        2. Vaccine Production
        3. Insulin Production
        4. Immunoglobulin Production
        5. Erythropoietin Production
        6. Other Applications (Interferons, Fusion Proteins, Growth Hormones, Blood Coagulation Factors, Anticoagulants, Medical Enzymes, Anti-bacterial (Antibiotics), and Colony Stimulating Factors)

  • 10.   Downstream Processing Market, By End User Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Biopharmaceutical Manufacturers
        2. Contract Manufacturing Organizations (CMOs)

  • 11.   North America Downstream Processing Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. U.S.A
         2.2. Canada
         2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2023-2031

  • 12.   Latin America Downstream Processing Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Brazil
         2.2. Venezuela
         2.3. Argentina
         2.4. Rest of Latin America
        3. Market Size (USD Million) Forecast for Latin America 2023-2031

  • 13.   Europe Downstream Processing Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Germany
         2.2. U.K
         2.3. France
         2.4. Italy
         2.5. Spain
         2.6. Russia
         2.7. Poland
         2.8. Rest of Europe
        3. Market Size (USD Million) Forecast for Europe 2023-2031

  • 14.   Asia Pacific Downstream Processing Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Japan
         2.2. China
         2.3. India
         2.4. Australia and New Zealand
         2.5. ASEAN
         2.6. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2023-2031

  • 15.   Middle East and Africa Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. GCC
         2.2. Israel
         2.3. South Africa
         2.4. Rest of MEA
        3. Market Size (USD Million) Forecast for MEA 2023-2031

  • 16.   Market Share Analysis and Competitive Landscape
    •   1. Global Landscape - Key Players, Revenue and Presence
        2. Global Share Analysis - Key Players (Tier 1, Tier 2, Tier 3)
        3. Global Emerging Companies
        4. North America - Market Share Analysis and Key Regional Players
        5. Europe - Market Share Analysis and Key Regional Players
        6. Asia Pacific - Market Share Analysis and Key Regional Players
        7. Global Key Player - Growth Matrix
  • 17.   Company Profiles (Competition Dashboard, Competitors Deep Dive, Products Offered and Financial Layouts)
    •   1. Thermo Fisher Scientific Inc.
         1.1. Company Overview
         1.2. Product Portfolio
         1.3. SWOT Analysis
         1.4. Financial Overview
         1.5. Strategic Overview
        2. GE Healthcare
         2.1. Company Overview
         2.2. Product Portfolio
         2.3. SWOT Analysis
         2.4. Financial Overview
         2.5. Strategic Overview
        3. Sartorius Stedim Biotech S.A.
         3.1. Company Overview
         3.2. Product Portfolio
         3.3. SWOT Analysis
         3.4. Financial Overview
         3.5. Strategic Overview
        4. Merck Millipore
         4.1. Company Overview
         4.2. Product Portfolio
         4.3. SWOT Analysis
         4.4. Financial Overview
         4.5. Strategic Overview
        5. Danaher Corporation
         5.1. Company Overview
         5.2. Product Portfolio
         5.3. SWOT Analysis
         5.4. Financial Overview
         5.5. Strategic Overview
        6. Repligen
         6.1. Company Overview
         6.2. Product Portfolio
         6.3. SWOT Analysis
         6.4. Financial Overview
         6.5. Strategic Overview
        7. 3M Company
         7.1. Company Overview
         7.2. Product Portfolio
         7.3. SWOT Analysis
         7.4. Financial Overview
         7.5. Strategic Overview
        8. Boehringer Ingelheim International GmbH
         8.1. Company Overview
         8.2. Product Portfolio
         8.3. SWOT Analysis
         8.4. Financial Overview
         8.5. Strategic Overview
        9. Corning Corporation
         9.1. Company Overview
         9.2. Product Portfolio
         9.3. SWOT Analysis
         9.4. Financial Overview
         9.5. Strategic Overview
        10. Lonza Group Ltd
         10.1. Company Overview
         10.2. Product Portfolio
         10.3. SWOT Analysis
         10.4. Financial Overview
         10.5. Strategic Overview
        11. Dover Corporation
         11.1. Company Overview
         11.2. Product Portfolio
         11.3. SWOT Analysis
         11.4. Financial Overview
         11.5. Strategic Overview
        12. Ashai Kasei
         12.1. Company Overview
         12.2. Product Portfolio
         12.3. SWOT Analysis
         12.4. Financial Overview
         12.5. Strategic Overview
        13. Ferner PLC
         13.1. Company Overview
         13.2. Product Portfolio
         13.3. SWOT Analysis
         13.4. Financial Overview
         13.5. Strategic Overview
        14. Eppendorf A
         14.1. Company Overview
         14.2. Product Portfolio
         14.3. SWOT Analysis
         14.4. Financial Overview
         14.5. Strategic Overview

  • 18.   Pre and Post COVID-19 Impact
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the healthcare regulations initiated by administrations
        5. The overall economic slowdown of the developing and developed nations
  • 19.   FutureWise SME Key Takeaway Points for Client
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