Overview


According to FutureWise analysis the market for downstream bioprocessing controllers in 2023 is US$ 1.39 billion, and is expected to reach US$ 5.05 billion by 2031 at a CAGR of 17.50%.

Rising insistence for biopharmaceuticals, increased acceptance of single-use technology, expansion of the capacity by the companies manufacturing biopharmaceutical products are some of the key factors driving the market growth. Furthermore, rising penetration of large molecules and biologics shall increase the acceptance of downstream methods, thereby proliferating the market. Purity, reasonable unit cost and efficacy are some of the key parameters to be considered for producing drugs. Downstream technique is often used in both industrial as well as lab applications due to an escalated insistence for biologics, which shall augment the downstream bioprocessing controllers market growth.

High throughput in the development process, perfusion chromatography, usage of data analytics and affinity chromatography are some of the crucial developments in downstream processing. Furthermore, the advantages related to the single use technology like substantial reduction in the facility construction time and capital cost which shall accelerate the growth of the market. Other benefits like improves mobility, increased scalability, eliminating cross contamination risk, reduced demand for sterilization and cleaning and high productivity shall boost the demand for downstream method significantly. The key market players are initiating multiple research and development activities for cutting down the total production cost, thereby minimizing the cost of retail products. These activities have escalated the investments in biotech research, thereby shortening the time of processing and the scope of throughput.

  • Merck Group
  • Danaher Corporation
  • GE Healthcare
  • ARTeSYN Biosolutions Ireland Ltd
  • Sepragen Corporation
  • Parker-Hannifin Corporation
  • 3M Company
  • VERDOT Ips²
  • Repligen Corporation
  • Sartorius

(Note: The list of the major players will be updated with the latest market scenario and trends)

By Procedure

  • Chromatography
  • Tangential Flow Filtration

By Product

  • Chromatography Controller System
  • TFF Controller System
  • Disposable Floe Path

By Application

  • Commercial Bioprocessing
    • Monoclonal Antibody Production
    • Therapeutic Protein Production
    • Vaccine Production
    • Cell and Gene Therapy
  • Research Bioprocessing

By End User

  • Pharmaceutical and Biotechnology Companies
  • Academic and Research Institutes
  • Contract Research Organizations
  • Food and Beverage Companies

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

The market is classified into procedure, product, application, end user and region. The procedure segment is fragmented into chromatography and tangential flow filtration. The tangential flow filtration procedure is predicted to hold the largest downstream bioprocessing controllers market share owing to a rise in the acceptance of tangential flow filtration processes for removing biofilm, bioburden and reducing endotoxin from biopharmaceutical fluids and all this with no effect on the product quality. Product-wise, the market is divided into chromatography controller system, TFF controller system, disposable flow path. The TFF products like disposable flow path dominated the market and this can be credited to an increased acceptance of TFF processes implemented with single use technology in meeting the rising insistence for concentrated protein with reduced time and capital investment. The application segment is divided into commercial bioprocessing and research bioprocessing. The commercial bioprocessing segment is fragmented into monoclonal antibody production, therapeutic protein production, vaccine production and cell and gene therapy. The commercial bioprocessing is predicted to lead the market and this mainly due to increased insistence for biopharmaceutical products, rise in the number of approvals for antibody products. The end user segment is categorised into pharmaceutical and biotechnology companies, contract manufacturing organization and academic and research institutes. The pharmaceutical and biotechnology companies led the market, and this can be credited to a high rate of consumption of bioprocessing consumables and equipment by these companies.

The North America region is anticipated to dominate the market owing to the advancements in downstream technology and a strong presence of key biopharmaceutical companies in the region. Furthermore, the government has heavily invested in the research and development activities pertaining to bioprocessing controllers which has boosted the market growth in the region. The Asia Pacific region is expected to grow at a substantial rate during the forecast period with key players expanding their businesses in the region. For instance, JHL Biotech of Taiwan uses modular SUT that is provided by GE Healthcare Life Sciences for constructing a biopharma facility in the province of Wuhan, China. There has been a rise in the number of approvals of biologics in developing and developed countries like China, Japan. For example, Chugai Pharmaceutical Co. Ltd. from Japan and the National Cancer Center, Japan has signed a research agreement for the project Master Key which shall promote R D in genomic medicines and cancer medicines.

  • Tier 1 players-established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants

  • Growth prospects
  • SWOT analysis
  • Key market trends
  • Key data-points affecting market growth

  • To provide with an exhaustive analysis on the global Downstream Bioprocessing Controllers Market By Procedure, By Product, By Application, By End User and By Region
  • To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
  • To evaluate and forecast micro-markets and the overall market
  • To predict the market size, in key regions (along with countries)—North America, Europe, Asia Pacific, Latin America and Middle East and Africa
  • To record, evaluate and analyze competitive landscape mapping-product launches, technological advancements, mergers and expansions

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Table of Contents


  • 1.   Market Introduction
    •   1. Objectives of the Study
        2. Market Definition
        3. Market Scope
         3.1. Years Considered for the Study
         3.2. Market Covered
        4. Currency
        5. Limitations
        6. Stakeholders
  • 2.   Research Methodology
    •   1. Research Data
         1.1. Secondary Data
          1.1.1. Key Data from Secondary Sources
         1.2. Primary Data
          1.2.1. Key Data from Primary Sources
        2. Market Size Estimation
        3. Market Breakdown and Data Triangulation
        4. Assumptions for the Study
  • 3.   Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights
  • 4.   Downstream Bioprocessing Controllers Market Variables, Trends and Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Technology Overview
        6. Regulatory Framework
         6.1. Reimbursement Framework
         6.2. Standards and Compliances

  • 5.   Market Overview
    •   1. Market Dynamics
         1.1. Market Driver Analysis
          1.1.1. Increasing focus of Downstream Bioprocessing Controllers Market Companies on Brand Protection
          1.1.2. Untapped Opportunities in Emerging Regions
         1.2. Market Restraint Analysis
          1.2.1. High Cost Associated with Implementation of Predictive Analysis
         1.3. Industry Challenges
          1.3.1. Presence of Ambiguous Regulatory Framework
  • 6.   Downstream Bioprocessing Controllers Market Analysis Tools
    •   1. Industry Analysis - Porter’s
         1.1. Supplier Power
         1.2. Buyer Power
         1.3. Substitution Threat
         1.4. Threat from New Entrants
         1.5. Competitive Rivalry
        2. Pestel Analysis
         2.1. Political Landscape
         2.2. Environmental Landscape
         2.3. Social Landscape
         2.4. Technology Landscape
         2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
         3.1. Joint Ventures
         3.2. Mergers and Acquisitions
         3.3. Licensing and Partnership
         3.4. Technology Collaborations
         3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies
  • 7.   Downstream Bioprocessing Controllers Market, By Procedure Historical Analysis 2017-2022 and Forecast 2023-2031 (USD million)
    •   1. Chromatography
        2. Tangential Flow Filtration

  • 8.   Downstream Bioprocessing Controllers Market, By Product Historical Analysis 2017-2022 and Forecast 2023-2031 (USD million)
    •   1. Chromatography Controller System
        2. TFF Controller System
        3. Disposable Floe Path

  • 9.   Downstream Bioprocessing Controllers Market, By Application Historical Analysis 2017-2022 and Forecast 2023-2031 (USD million)
    •   1. Commercial Bioprocessing
         1.1 . Monoclonal Antibody Production
         1.2 . Therapeutic Protein Production
         1.3 . Vaccine Production
         1.4 . Cell and Gene Therapy
        2. Research Bioprocessing

  • 10.   Downstream Bioprocessing Controllers Market, By End User Historical Analysis 2017-2022 and Forecast 2023-2031 (USD million)
    •   1 . Pharmaceutical and Biotechnology Companies
        2 . Academic and Research Institutes
        3 . Contract Research Organizations
        4 . Food and Beverage Companies

  • 11.   North America Downstream Bioprocessing Controllers Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. U.S.A
         2.2. Canada
         2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2023-2031

  • 12.   Latin America Downstream Bioprocessing Controllers Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Brazil
         2.2. Venezuela
         2.3. Argentina
         2.4. Rest of Latin America
        3. Market Size (USD Million) Forecast for Latin America 2023-2031

  • 13.   Europe Downstream Bioprocessing Controllers Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Germany
         2.2. U.K
         2.3. France
         2.4. Italy
         2.5. Spain
         2.6. Russia
         2.7. Poland
         2.8. Rest of Europe
        3. Market Size (USD Million) Forecast for Europe 2023-2031

  • 14.   Asia Pacific Downstream Bioprocessing Controllers Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Japan
         2.2. China
         2.3. India
         2.4. Australia and New Zealand
         2.5. ASEAN
         2.6. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2023-2031

  • 15.   Middle East and Africa Downstream Bioprocessing Controllers Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. GCC
         2.2. Israel
         2.3. South Africa
         2.4. Rest of MEA
        3. Market Size (USD Million) Forecast for MEA 2023-2031

  • 16.   Market Share Analysis and Competitive Landscape
    •   1. Global Landscape - Key Players, Revenue and Presence
        2. Global Share Analysis - Key Players (Tier 1, Tier 2, Tier 3)
        3. Global Emerging Companies
        4. North America - Market Share Analysis and Key Regional Players
        5. Europe - Market Share Analysis and Key Regional Players
        6. Asia Pacific - Market Share Analysis and Key Regional Players
        7. Global Key Player - Growth Matrix
  • 17.   Company Profiles (Competition Dashboard, Competitors Deep Dive, Products Offered and Financial Layouts)
    •   1. Merck Group
         1.1. Company Overview
         1.2. Product Portfolio
         1.3. SWOT Analysis
         1.4. Financial Overview
         1.5. Strategic Overview
        2. Danaher Corporation
         2.1. Company Overview
         2.2. Product Portfolio
         2.3. SWOT Analysis
         2.4. Financial Overview
         2.5. Strategic Overview
        3. GE Healthcare
         3.1. Company Overview
         3.2. Product Portfolio
         3.3. SWOT Analysis
         3.4. Financial Overview
         3.5. Strategic Overview
        4. ARTeSYN Biosolutions Ireland Ltd
         4.1. Company Overview
         4.2. Product Portfolio
         4.3. SWOT Analysis
         4.4. Financial Overview
         4.5. Strategic Overview
        5. Sepragen Corporation
         5.1. Company Overview
         5.2. Product Portfolio
         5.3. SWOT Analysis
         5.4. Financial Overview
         5.5. Strategic Overview
        6. Parker-Hannifin Corporation
         6.1. Company Overview
         6.2. Product Portfolio
         6.3. SWOT Analysis
         6.4. Financial Overview
         6.5. Strategic Overview
        7. 3M Company
         7.1. Company Overview
         7.2. Product Portfolio
         7.3. SWOT Analysis
         7.4. Financial Overview
         7.5. Strategic Overview
        8. VERDOT Ips²
         8.1. Company Overview
         8.2. Product Portfolio
         8.3. SWOT Analysis
         8.4. Financial Overview
         8.5. Strategic Overview
        9. Repligen Corporation
         9.1. Company Overview
         9.2. Product Portfolio
         9.3. SWOT Analysis
         9.4. Financial Overview
         9.5. Strategic Overview
        10. Sartorius AG
         10.1. Company Overview
         10.2. Product Portfolio
         10.3. SWOT Analysis
         10.4. Financial Overview
         10.5. Strategic Overview

  • 18.   Pre and Post COVID-19 Impact
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the healthcare regulations initiated by
                  administrations
        5. The overall economic slowdown of the developing and developed nations

  • 19.   FutureWise SME Key Takeaway Points for Client
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