Overview


As the third most commonly diagnosed cancer worldwide, and the second most lethal, colorectal cancer (CRC) is one of the most common diseases worldwide. Despite its value in guiding clinical management of colorectal cancer patients, solid biopsy carries several limitations, such as its invasiveness and inability to be used repeatedly. Clinical research directed toward the use of liquid biopsy, as an alternative to solid biopsy, has shown significant promise in several CRC clinical applications recently, including detecting CRC patients at an early stage, deciding how to treat them, monitoring their response, predicting relapses and metastases, unraveling tumor heterogeneity, and detecting minimal residual disease. The purpose of this short review is to describe the concept, the characteristics, the genetic components, and the technologies used in liquid biopsy in the context of colorectal cancer management, and we reviewed gene alterations, recently described in the literature, as promising potential biomarkers that may be used specifically in liquid biopsy tests. Liquid biopsy provides a noninvasive method of collecting samples for analysis of circulating tumor cells (CTCs) and genomic material, such as cell-free DNA (cfDNA), as a complementary biopsy to solid tumor tissue. Solid biopsies are critical for molecular characterization and diagnosis at the time of collection. The liquid biopsy offers longitudinal molecular characterization of the disease, which is crucial for precision medicine and patient-centered care. We provide an overview of CRC and the different methodologies for detecting CTCs and cfDNA, followed by a discussion of the potential clinical utility of liquid biopsy in CRC patient care, and finally, current challenges. Increasing colorectal cancer cases and increasing demand for minimally invasive procedures and advanced cancer treatments are driving the growth of the colorectal cancer liquid biopsy market. Additionally, the increase in healthcare expenditures, the availability of skilled professionals, the increase in R D activities to develop and launch novel therapies, and technological advancements in the field of oncology boost the colorectal cancer liquid biopsy market. Recent advances have not yet achieved the desired specificity and sensitivity. The growth of the market may be hindered by this factor. The growing interest in liquid biopsy, however, may offer new opportunities for the industry

FutureWise Market Research has instantiated a report that provides an intricate analysis of Colorectal Cancer Liquid Biopsy Market trends that shall affect the overall market growth. Furthermore, it includes detailed information on the graph of profitability, SWOT analysis, market share and regional proliferation of this business. Moreover, the report offers insights on the current stature of prominent market players in the competitive landscape analysis of this market.

According to the research study conducted by FutureWise research analysts, the Colorectal Cancer Liquid Biopsy Market is anticipated to attain substantial growth by the end of the forecast period. The report explains that this business is predicted to register a noteworthy growth rate over the forecast period. This report provides crucial information pertaining to the total valuation that is presently held by this industry and it also lists the segmentation of the market along with the growth opportunities present across this business vertical.

  • Guardant health
  • NeoLAB
  • Biocept Inc
  • Qigen
  • F.hoffmann-La Roche AG
  • Bio-rad Laboratories Inc
  • Myriad genetics
  • Janseen Diagnostics
  • Trovagene Inc
  • Guardant health Inc
  • GRAIL and MDX Health SA

(Note: The list of the major players will be updated with the latest market scenario and trends)

By Biomarker Type

  • Circulating Tumor cells
  • Circulating Tumor DNA
  • Extracellular Vesicles

By Products

  • Kits & Reagents
  • Platforms & Instruments
  • Services

By End-User

  • Diagnostic & Imaging Centers
  • Hospitals
  • Academics & Research Centers
  • Others

By Region

  • Tier 1 players- established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants

  • Growth prospects
  • SWOT analysis
  • Key trends
  • Key data-points affecting market growth

  • To provide with an exhaustive analysis on the Colorectal Cancer Liquid Biopsy Market By Biomarker Type, By Products & Services, By End-User and By Region.
  • To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
  • To evaluate and forecast micro-markets and the overall market
  • To predict the market size, in key regions— North America, Europe, Asia Pacific, Latin America and Middle East and Africa.
  • To record and evaluate competitive landscape mapping- product launches, technological advancements, mergers and expansions

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  • The customization Mobility Care offered are free of charge with purchase of any license of the report
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Table of Contents


  • 1.   Market Introduction
    •   1. Objectives of the Study
        2. Market Definition
        3. Market Scope
         3.1. Years Considered for the Study
         3.2. Market Covered
        4. Currency
        5. Limitations
        6. Stakeholders
  • 2.   Research Methodology
    •   1. Research Data
         1.1. Secondary Data
          1.1.1. Key Data from Secondary Sources
         1.2. Primary Data
          1.2.1. Key Data from Primary Sources
        2. Market Size Estimation
        3. Market Breakdown and Data Triangulation
        4. Assumptions for the Study
  • 3.   Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights
  • 4.   Colorectal Cancer Liquid Biopsy Market Variables, Trends and Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Technology Overview
        6. Regulatory Framework
         6.1. Reimbursement Framework
         6.2. Standards and Compliances

  • 5.   Market Overview
    •   1. Market Dynamics
         1.1. Market Driver Analysis
          1.1.1. Increasing focus of Colorectal Cancer Liquid Biopsy Market Companies on Brand Protection
          1.1.2. Untapped Opportunities in Emerging Regions
         1.2. Market Restraint Analysis
          1.2.1. High Cost Associated with Implementation of Predictive Analysis
         1.3. Industry Challenges
          1.3.1. Presence of Ambiguous Regulatory Framework
  • 6.   Colorectal Cancer Liquid Biopsy Market Analysis Tools
    •   1. Industry Analysis - Porter’s
         1.1. Supplier Power
         1.2. Buyer Power
         1.3. Substitution Threat
         1.4. Threat from New Entrants
         1.5. Competitive Rivalry
        2. Pestel Analysis
         2.1. Political Landscape
         2.2. Environmental Landscape
         2.3. Social Landscape
         2.4. Technology Landscape
         2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
         3.1. Joint Ventures
         3.2. Mergers and Acquisitions
         3.3. Licensing and Partnership
         3.4. Technology Collaborations
         3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies
  • 7.   Colorectal Cancer Liquid Biopsy Market, By Biomarker Type Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Circulating Tumor cells
        2. Circulating Tumor DNA
        3. Extracellular Vesicles

  • 8.   Colorectal Cancer Liquid Biopsy Market, By Products & Services Historical Analysis and Forecast 2023-2031 (USD Million)
    •     1. Kits & Reagents
        2. Platforms & Instruments
        3. Services

  • 9.   Colorectal Cancer Liquid Biopsy Market, By End-User Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Diagnostic & Imaging Centers
        2. Hospitals
        3. Academics & Research Centers
        4. Others

  • 10.   North America Colorectal Cancer Liquid Biopsy Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. U.S.A
         2.2. Canada
         2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2023-2031

  • 11.   Latin America Colorectal Cancer Liquid Biopsy Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Brazil
         2.2. Venezuela
         2.3. Argentina
         2.4. Rest of Latin America
        3. Market Size (USD Million) Forecast for Latin America 2023-2031

  • 12.   Europe Colorectal Cancer Liquid Biopsy Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Germany
         2.2. U.K
         2.3. France
         2.4. Italy
         2.5. Spain
         2.6. Russia
         2.7. Poland
         2.8. Rest of Europe
        3. Market Size (USD Million) Forecast for Europe 2023-2031

  • 13.   Asia Pacific Colorectal Cancer Liquid Biopsy Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Japan
         2.2. China
         2.3. India
         2.4. Australia and New Zealand
         2.5. ASEAN
         2.6. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2023-2031

  • 14.   Middle East and Africa Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. GCC
         2.2. Israel
         2.3. South Africa
         2.4. Rest of MEA
        3. Market Size (USD Million) Forecast for MEA 2023-2031

  • 15.   Market Share Analysis and Competitive Landscape
    •   1. Global Landscape - Key Players, Revenue and Presence
        2. Global Share Analysis - Key Players (Tier 1, Tier 2, Tier 3)
        3. Global Emerging Companies
        4. North America - Market Share Analysis and Key Regional Players
        5. Europe - Market Share Analysis and Key Regional Players
        6. Asia Pacific - Market Share Analysis and Key Regional Players
        7. Global Key Player - Growth Matrix
  • 16.   Company Profiles (Competition Dashboard, Competitors Deep Dive, Products Offered and Financial Layouts)
    •   1. Guardant health
         1.1. Company Overview
         1.2. Product Portfolio
         1.3. SWOT Analysis
         1.4. Financial Overview
         1.5. Strategic Overview
        2. NeoLAB
         2.1. Company Overview
         2.2. Product Portfolio
         2.3. SWOT Analysis
         2.4. Financial Overview
         2.5. Strategic Overview
        3. Biocept Inc
         3.1. Company Overview
         3.2. Product Portfolio
         3.3. SWOT Analysis
         3.4. Financial Overview
         3.5. Strategic Overview
        4. Qigen
         4.1. Company Overview
         4.2. Product Portfolio
         4.3. SWOT Analysis
         4.4. Financial Overview
         4.5. Strategic Overview
        5. F.hoffmann-La Roche AG
         5.1. Company Overview
         5.2. Product Portfolio
         5.3. SWOT Analysis
         5.4. Financial Overview
         5.5. Strategic Overview
        6. Bio-rad Laboratories Inc
         6.1. Company Overview
         6.2. Product Portfolio
         6.3. SWOT Analysis
         6.4. Financial Overview
         6.5. Strategic Overview
        7. Myriad genetics
         7.1. Company Overview
         7.2. Product Portfolio
         7.3. SWOT Analysis
         7.4. Financial Overview
         7.5. Strategic Overview
        8. Janseen Diagnostics
         8.1. Company Overview
         8.2. Product Portfolio
         8.3. SWOT Analysis
         8.4. Financial Overview
         8.5. Strategic Overview
        9. Trovagene Inc
         9.1. Company Overview
         9.2. Product Portfolio
         9.3. SWOT Analysis
         9.4. Financial Overview
         9.5. Strategic Overview
        10.Guardant health Inc
         10.1. Company Overview
         10.2. Product Portfolio
         10.3. SWOT Analysis
         10.4. Financial Overview
         10.5. Strategic Overview
        11.GRAIL and MDX Health SA
         11.1. Company Overview
         11.2. Product Portfolio
         11.3. SWOT Analysis
         11.4. Financial Overview
         11.5. Strategic Overview

  • 17.   Pre and Post COVID-19 Impact
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the regulations initiated by healthcare administrations
        5. The overall economic slowdown of the developing and developed nations
  • 18.   FutureWise SME Key Takeaway Points for Client
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