Overview


According to FutureWise analysis the market for bone graft substitutes in 2023 is US$ 3.8 billion, and is expected to reach US$ 6.25 billion by 2031 at a CAGR of 6.40%.

Bone is a flexible organ with exceptional regeneration abilities. However, healthy bones need osteoblasts, osteoclasts, and osteocytes, as well as appropriate vascularity, stability, growth hormones, and a growth matrix. However, there are many circumstances where one or more of these requirements are not met, necessitating surgeons' aid in promoting bone healing. Bone grafting is frequently utilized to create an osteoconductive, osteoinductive, and/or osteogenic environment to encourage bone healing and repair when the process of bone repair needs additional support.

Bone flaws are a growing clinical issue in orthopedic and trauma surgery on a regular basis. These are brought on by tumors and bone infections, which typically call for surgical removal and subsequent skeletal repair. Additionally, bone deficiencies commonly accompany fractures following high-energy trauma and osteoporotic fractures, necessitating operations for bone augmentation. The main cause of a predicted rise in bone abnormalities is osteoporotic fractures. Autografts, allografts, and biomaterial-based bone graft substitutes using ceramics, synthetic polymers, or natural polymers can all be used for bone defect restoration. Along with being osteogenic, autografts can also be osteoconductive and osteoinductive. However, limitations in supply, morbidity at the donor site, and longer recovery times are challenges with using autologous bone grafts.

FutureWise Market Research has published a report that provides an insightful analysis of bone graft substitutes market trends that are affecting the overall market growth. This report will provide a detailed analysis of market share, regional insights, and competitor analysis that includes stature of key manufacturers operational in this industry. According to the analysis conducted by FutureWise research analysts, the bone graft substitutes market is estimated to register a considerable growth rate over the forecast period. this report lists the market segments and potential prospects available across this industry, in addition providing crucial information on the total valuation currently held by the industry. Moreover, this report will assist key management individuals in an organisation to enhance their decisions pertaining to business expansion as well as strategic changes for increasing customer base.

  • NovaBone Product, LLC.
  • Exactech, Inc.
  • Medtronic Plc.
  • LifeNet Health
  • Zimmer Biomet Holdings, Inc.
  • Stryker Corporation.
  • BioHorizons Implant Systems, Inc.
  • Globus Medical, Inc.
  • RTI Surgical, Inc
  • Geistlich Pharma
  • Megagen
  • Novadip Biosciences
  • Mesoblast Ltd.
  • Alphatec Spine, Inc.
  • Institut Straumann AG
  • NuVasive, Inc.
  • OsteoMed LLC
  • KYERON Medical Innovations

(Note: The list of the major players will be updated with the latest market scenario and trends)

Recent developments by key players in Bone Graft Substitutes Market:

In March 2022- Osteo-P Synthetic Bone Graft Substitute (BGS) was introduced by Molecular Matrix, Inc. for use in the musculoskeletal system. Osteo-P BGS is created by utilizing Molecular Matrix's hyper-crosslinked carbohydrate polymer (HCCP) technology platform, engineered to optimize the bone repair and regeneration microenvironment.

Bone autografts continue to be the gold standard because there are no concerns about histocompatibility or the spread of disease and because of their exceptional osteogenicity, osteoconductivity, and osteoinductivity characteristics. However, the use of artificial substitutes, such as calcium phosphate ceramics, which can be produced in the required volumes and produce excellent results without the problem of donor site morbidity seen with autografts, is becoming a viable option for therapy. Additionally, advancements in fields like three-dimensional printing and bone tissue engineering are producing positive results and may open the door for better treatment during the anticipated period. Moreover, the market for dental bone graft alternatives is anticipated to grow as a result of rising consumer demand and a growing desire for cosmetic dentistry. The market is expanding due to rising dental bone transplant demand and technological improvements. The demand for biocompatible bone grafts to reduce adverse reactions is also driving the market's expansion. However, depending on the patient and the situation, a bone graft might cost anywhere from thousands to millions of dollars. For example, a single implant location for simple synthetic bone grafting will cost between USD 300 and USD 800. The cost of the bone graft process increases when a bone is extracted from various locations on the patient's body, necessitating hospitalization. The market for bone graft substitutes may be hampered by the high cost of bone grafting with various materials tailored to the patient's needs.

By Product

  • Allografts
  • Demineralized Bone Matrix (DBM)
  • Synthetic Bone Graft
    • Polymer
    • Ceramic
    • Hydroxyapatite
    • Beta TCP
  • Xenograft
  • Autograft

By Material

  • Ceramic-based
    • Calcium Phosphate
    • Calcium Sulfate
  • Polymer-based
    • Polylactides
    • Polyglycolides
    • Polyurethanes
    • Others
  • Growth Factor-based
  • Cell-based
  • Others

By Application

  • Craniomaxillofacial
  • Dental
  • Foot And Ankle
  • Joint Reconstruction
  • Spinal Fusion
  • Long Bones
  • Others

By End User

  • Hospitals
  • Clinics
  • Ambulatory Care Centers
  • Academic And Research Institutes

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

This market research report also emphasis on factors affecting the growth rate in various regions listed above. A deep-down analysis of region will also be provided in the final version of this market which is based on conclusion of primary interviews and secondary data point gathered during the process.

By region, the market is segmented into North America, Latin America, Europe, Asia-Pacific, and Middle East & Africa. North America registered the highest share in the market in 2022. Due to well-established healthcare infrastructure, rising technological innovation, rising prevalence of joint illnesses and dental ailments, growing dental visits, and other variables. Increased demand for bone grafting procedures to stop small bones from grinding against each other to provide relief and remove the inflamed bone from the area is likely to result from the rising burden of dental diseases and joint-related disorders such as osteoarthritis, arthritis, and rheumatoid arthritis among the population, which is likely to drive market growth.

Additionally, based on product, Allografts dominated the market in 2022. Allograft use is expanding due to its advantages, including osteoconductivity and rapid structural support. They also don't need a second surgery, which speeds up wound healing and reduces surgical time.

  • Tier 1 players- established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants

  • Growth prospects
  • SWOT analysis
  • Key trends
  • Key data-points affecting market growth

  • To provide with an exhaustive analysis on the Bone Graft Substitutes Market By Product, By Material, By Application, By End User and By Region.
  • To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
  • To evaluate and forecast micro-markets and the overall market
  • To predict the market size, in key regions— North America, Europe, Asia Pacific, Latin America and Middle East and Africa.
  • To record and evaluate competitive landscape mapping- Product launches, technological advancements, mergers and expansions

  • We have a flexible delivery model and you can suggest changes in the scope/table of content as per your requirement
  • The customization Mobility Care offered are free of charge with purchase of any license of the report
  • You can directly share your requirements/changes to the current table of content to: sales@futurewiseresearch.com

Table of Contents


  • 1.   Market Introduction
    •   1. Objectives of the Study
        2. Market Definition
        3. Market Scope
         3.1. Years Considered for the Study
         3.2. Market Covered
        4. Currency
        5. Limitations
        6. Stakeholders

  • 2.   Research Methodology
    •   1. Research Data
         1.1. Secondary Data
          1.1.1. Key Data from Secondary Sources
         1.2. Primary Data
          1.2.1. Key Data from Primary Sources
        2. Market Size Estimation
        3. Market Breakdown and Data Triangulation
        4. Assumptions for the Study

  • 3.   Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights
  • 4.   Global Bone Graft Substitutes Market Variables, Trends and Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Technology Overview
        6. Regulatory Framework
         6.1. Reimbursement Framework
         6.2. Standards and Compliances

  • 5.   Market Overview
    •   1. Market Dynamics
         1.1. Market Driver Analysis
          1.1.1. Increasing focus of Bone Graft Substitutes Market Companies on Brand Protection
          1.1.2. Untapped Opportunities in Emerging Regions
         1.2. Market Restraint Analysis
          1.2.1. High Cost Associated with Implementation of Predictive Analysis
         1.3. Industry Challenges
          1.3.1. Presence of Ambiguous Regulatory Framework
  • 6.   Global Bone Graft Substitutes Market Analysis Tools
    •   1. Industry Analysis - Porter’s
         1.1. Supplier Power
         1.2. Buyer Power
         1.3. Substitution Threat
         1.4. Threat from New Entrants
         1.5. Competitive Rivalry
        2. Pestel Analysis
         2.1. Political Landscape
         2.2. Environmental Landscape
         2.3. Social Landscape
         2.4. Technology Landscape
         2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
         3.1. Joint Ventures
         3.2. Mergers and Acquisitions
         3.3. Licensing and Partnership
         3.4. Technology Collaborations
         3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies
  • 7.   Global Bone Graft Substitutes Market, By Product Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Allografts
        2. Demineralized Bone Matrix (DBM)
        3. Synthetic Bone Graft
         3.1. Polymer
         3.2. Ceramic
          3.2.1. Hydroxyapatite
          3.2.2. Beta TCP
        4. Xenograft
        5. Autograft

  • 8.   Global Bone Graft Substitutes Market, By Material Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Ceramic-based
         1.1. Calcium Phosphate
         1.2. Calcium Sulfate
        2. Polymer-based
         2.1. Polylactides
         2.2. Polyglycolides
         2.3. Polyurethanes
         2.4. Others
        3. Growth Factor-based
        4. Cell-based
        5. Others

  • 9.   Global Bone Graft Substitutes Market, By Application Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Craniomaxillofacial
        2. Dental
        3. Foot And Ankle
        4. Joint Reconstruction
        5. Spinal Fusion
        6. Long Bones
        7. Others

  • 10.   Global Bone Graft Substitutes Market, By End User Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Hospitals
        2. Clinics
        3. Ambulatory Care Centers
        4. Academic And Research Institutes

  • 11.   North America Bone Graft Substitutes Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. U.S.A
         2.2. Canada
         2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2023-2031

  • 12.   Latin America Bone Graft Substitutes Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Brazil
         2.2. Venezuela
         2.3. Argentina
         2.4. Rest of Latin America
        3. Market Size (USD Million) Forecast for Latin America 2023-2031

  • 13.   Europe Bone Graft Substitutes Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Germany
         2.2. U.K
         2.3. France
         2.4. Italy
         2.5. Spain
         2.6. Russia
         2.7. Poland
         2.8. Rest of Europe
        3. Market Size (USD Million) Forecast for Europe 2023-2031

  • 14.   Asia Pacific Bone Graft Substitutes Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Japan
         2.2. China
         2.3. India
         2.4. Australia and New Zealand
         2.5. ASEAN
         2.6. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2023-2031

  • 15.   Middle East and Africa Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Saudi Arabia
         2.2. UAE
         2.3. South Africa
         2.4. Egypt
        3. Market Size (USD Million) Forecast for MEA 2023-2031

  • 16.   Market Share Analysis and Competitive Landscape
    •   1. Global Landscape - Key Players, Revenue and Presence
        2. Global Share Analysis - Key Players (Tier 1, Tier 2, Tier 3)
        3. Global Emerging Companies
        4. North America - Market Share Analysis and Key Regional Players
        5. Europe - Market Share Analysis and Key Regional Players
        6. Asia Pacific - Market Share Analysis and Key Regional Players
        7. Global Key Player - Growth Matrix
  • 17.   Company Profiles (Competition Dashboard, Competitors Deep Dive, Products Offered and Financial Layouts)
    •   1. NovaBone Product, LLC.
         1.1. Company Overview
         1.2. Product Portfolio
         1.3. SWOT Analysis
         1.4. Financial Overview
         1.5. Strategic Overview
        2. Exactech, Inc.
         2.1. Company Overview
         2.2. Product Portfolio
         2.3. SWOT Analysis
         2.4. Financial Overview
         2.5. Strategic Overview
        3. Medtronic Plc.
         3.1. Company Overview
         3.2. Product Portfolio
         3.3. SWOT Analysis
         3.4. Financial Overview
         3.5. Strategic Overview
        4. LifeNet Health
         4.1. Company Overview
         4.2. Product Portfolio
         4.3. SWOT Analysis
         4.4. Financial Overview
         4.5. Strategic Overview
        5. Zimmer Biomet Holdings, Inc.
         5.1. Company Overview
         5.2. Product Portfolio
         5.3. SWOT Analysis
         5.4. Financial Overview
         5.5. Strategic Overview
        6. Stryker Corporation.
         6.1. Company Overview
         6.2. Product Portfolio
         6.3. SWOT Analysis
         6.4. Financial Overview
         6.5. Strategic Overview
        7. BioHorizons Implant Systems, Inc.
         7.1. Company Overview
         7.2. Product Portfolio
         7.3. SWOT Analysis
         7.4. Financial Overview
         7.5. Strategic Overview
        8. Globus Medical, Inc.
         8.1. Company Overview
         8.2. Product Portfolio
         8.3. SWOT Analysis
         8.4. Financial Overview
         8.5. Strategic Overview
        9. RTI Surgical, Inc
         9.1. Company Overview
         9.2. Product Portfolio
         9.3. SWOT Analysis
         9.4. Financial Overview
         9.5. Strategic Overview
        10. Geistlich Pharma
         10.1.Company Overview
         10.2.Product Portfolio
         10.3.SWOT Analysis
         10.4.Financial Overview
         10.5.Strategic Overview
        11. Megagen
         11.1.Company Overview
         11.2.Product Portfolio
         11.3.SWOT Analysis
         11.4.Financial Overview
         11.5.Strategic Overview
        12. Novadip Biosciences
         12.1.Company Overview
         12.2.Product Portfolio
         12.3.SWOT Analysis
         12.4.Financial Overview
         12.5.Strategic Overview
        13. Mesoblast Ltd.
         13.1.Company Overview
         13.2.Product Portfolio
         13.3.SWOT Analysis
         13.4.Financial Overview
         13.5.Strategic Overview
        14. Alphatec Spine, Inc.
         14.1.Company Overview
         14.2.Product Portfolio
         14.3.SWOT Analysis
         14.4.Financial Overview
         14.5.Strategic Overview
        15. Institut Straumann AG
         15.1.Company Overview
         15.2.Product Portfolio
         15.3.SWOT Analysis
         15.4.Financial Overview
         15.5.Strategic Overview
        16. NuVasive, Inc.
         16.1.Company Overview
         16.2.Product Portfolio
         16.3.SWOT Analysis
         16.4.Financial Overview
         16.5.Strategic Overview
        17. OsteoMed LLC
         17.1.Company Overview
         17.2.Product Portfolio
         17.3.SWOT Analysis
         17.4.Financial Overview
         17.5.Strategic Overview
        18. KYERON Medical Innovations
         18.1.Company Overview
         18.2.Product Portfolio
         18.3.SWOT Analysis
         18.4.Financial Overview
         18.5.Strategic Overview

  • 18.   Pre and Post COVID-19 Impact
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the healthcare regulations initiated by administrations
        5. The overall economic slowdown of the developing and developed nations
  • 19.   FutureWise SME Key Takeaway Points for Client
Partner

Our Clients