Overview


According to FutureWise analysis, the market for Alpha 1 Lung Disease is expected to grow with a CAGR of 18.9% over the forecast period 2024-2032, and reach a market value of US$ 19.93 billion by 2031.

Alpha-1 lung disease, also known as Alpha-1 Antitrypsin Deficiency (AATD), is a congenital disorder that can lead to lung and liver disease. It is caused by a deficiency of a protein called alpha-1 antitrypsin (AAT), which is produced in the liver and helps protect the lungs from damage caused by enzymes released by white blood cells. When there is a deficiency of AAT, the enzymes can attack normal lung tissue, leading to disorders like chronic obstructive pulmonary disease and emphysema. In some severe circumstances, it can also lead to liver disease. It's essential to note that not everyone with alpha-1 antitrypsin deficiency will develop these complications, and the severity may vary widely among individuals. Smoking and environmental factors can also influence the progression of the disease.

The choice of route of administration relies on various factors, such as the type and severity of the condition, the properties of the medication, the patient's condition and preferences, and the desired onset and duration of action. The selection of the administration route is contingent upon diverse types such as inhalation, injection, and oral intake. Inhalation is direct delivery to the lungs, providing immediate absorption and quick onset of action for respiratory conditions. It reduces systemic side effects. Inhalers are for asthma or chronic obstructive pulmonary disease (COPD). Also, injectable (usually Intravenous - IV) delivers rapid and precise medication directly into the bloodstream. This can be crucial in emergencies or when immediate effects are needed. Antibiotics are taken for severe infections, chemotherapy drugs, and certain types of pain relief. For oral, it is easy, convenient, and generally well-tolerated by patients. It's the most common route of administration for many medications.

FutureWise Market Research has published a report that provides an insightful analysis alpha 1 lung disease market trends that are affecting the overall market growth. This report will provide a detailed analysis of market share, regional insights, and competitor analysis that includes stature of key manufacturers operational in this industry. According to the analysis conducted by FutureWise research analyst’s alpha 1 lung disease market estimated to register a considerable growth rate over the forecast period. This report lists the market segments and potential prospects available across this industry, in addition providing crucial information on the total valuation currently held by the industry. Moreover, this report will assist key management individuals in an organisation to enhance their decisions pertaining to business expansion as well as strategic changes for increasing customer base.

  • AstraZeneca 
  • Boehringer Ingelheim 
  • Roche
  • Novartis 
  • Pfizer
  • Merck
  • Bristol-Myers Squibb 
  • Takeda Pharmaceutical 
  • CSL Behring
  • Vertex Pharmaceuticals 
  • Amgen
  • Sanofi
  • GlaxoSmithKline
  • Gilead Sciences
  • Eli Lilly
  • AbbVie
  • Johnson & Johnson
  • Teva Pharmaceutical 
  • Audentes Therapeutics 
  • Regeneron Pharmaceuticals

(Note: The list of the major players will be updated with the latest market scenario and trends)

Recent Developments in Alpha 1 Lung Disease Market:

  • In July 2022, Vertex acquired ViaCyte's stem cell-derived cell replacement therapy assets for alpha-1 lung disease for potential cure.
  • In September 2021, Takeda received FDA approval for Livmarli, a new drug to treat alpha-1 lung disease. Livmarli reduces the accumulation of abnormal alpha-1 protein in the liver.

The rising incidence of the senior population presents a significant driver for the alpha-1 lung disease market. As individuals age, they may become more susceptible to genetic conditions and respiratory challenges, making early detection and treatment crucial. This demographic change necessitates a greater focus on screening and diagnostic initiatives. It underscores the importance of advancing therapeutic interventions customized to the specific needs of elderly patients afflicted with alpha-1 lung disease. Consequently, pharmaceutical companies and healthcare providers have an expanding patient base, further driving research, development, and innovation in the field to satisfy the demands of this senior population. Furthermore, the facilitation of regulatory approvals by various government agencies for novel therapies and product launches is expected to accelerate the Alpha-1 Lung Disease market. Streamlined approval processes and a supportive regulatory environment enable expedited market entry for innovative treatments, fostering a landscape ripe for advancements. This regulatory backing instills confidence in pharmaceutical innovators and ensures healthcare professionals and patient's safety and efficacy of these emerging therapies. For instance, in March 2023, Mereo BioPharma Group plc received positive feedback for its alvelestat program from the FDA and EMA for the treatment of alpha-1-antitrypsin deficiency associated with lung disease. However, the high cost associated with the treatment of alpha-1 lung disease imposes substantial barriers, especially for patients lacking sufficient insurance coverage. The specialized nature of treatments, including enzyme replacement therapies and comprehensive care plans, might result in high financial commitments. For those without robust insurance support, accessing these crucial interventions becomes difficult, potentially leading to delayed or inadequate care. This financial hindrance not only burdens concerned individuals and their families but also poses a systemic challenge to healthcare equity.

By Disease Type

  • Alpha-1 Antitrypsin Deficiency
  • Chronic Obstructive Pulmonary Disease (COPD)
  • Pulmonary Fibrosis
  • Bronchiectasis
  • Others

By Treatment Type

  • Augmentation Therapy
  • Bronchodilators
  • Corticosteroids
  • Oxygen Therapy
  • Lung Transplantation
  • Others

By Route of Administration

  • Inhalation
  • Injectable
  • Oral

By Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

By End User

  • Hospitals
  • Homecare
  • Specialty Clinics
  • Others

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

This market research report also emphasis on factors affecting the growth rate in various regions listed above. A deep-down analysis of region will also be provided in the final version of this market which is based on conclusion of primary interviews and secondary data point gathered during the process.

By region, the market is segmented into North America, Latin America, Europe, Asia-Pacific, and Middle East & Africa. North America registered highest share in the market in 2022. Due to factors like high diagnosis rates, favourable reimbursement policies, presence of key players, rising prevalence of COPD, increasing awareness, new product launches, and increasing diagnosis rates are likely to increase the demand for the alpha 1 lung disease market over the forecast period in the region. For instance, in May 2023, Kamada announced the launch of an inhaled version of its alpha-1 proteinase inhibitor drug, Glassia, in Europe. The drug is expected to improve outcomes for alpha-1 patients. In addition, robust healthcare infrastructure, presence of significant market competitors, continuous research and development initiatives, and regulatory approval by various government agencies for novel therapies. In March 2022, Inhibrx, Inc. received fast-track designation for its INBRX-101, which is a clinical trial for the treatment of alpha-1 antitrypsin deficiency.

  • Tier 1 players- established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants

  • Growth prospects
  • SWOT analysis
  • Key trends
  • Key data-points affecting market growth

  • To provide with an exhaustive analysis on the Alpha 1 Lung Disease Market By Disease Type, By Treatment Type, By Route of Administration, By Distribution Channel, By End User, and By Region
  • To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
  • To evaluate and forecast micro-markets and the overall market
  • To predict the market size, in key regions— North America, Europe, Asia Pacific, Latin America and Middle East and Africa.
  • To record and evaluate competitive landscape, mapping- product launches, technological advancements, mergers and expansions

  • We have a flexible delivery model and you can suggest changes in the scope/table of content as per your requirement
  • The customization Mobility Care offered are free of charge with purchase of any license of the report
  • You can directly share your requirements/changes to the current table of content to: sales@futurewiseresearch.com

Table of Contents


  • 1.  Market Introduction
    •   1. Objectives of the Study 
        2. Market Definition 
        3. Market Scope 
           3.1. Years Considered for the Study
           3.2. Market Covered
        4. Currency 
        5. Limitations 
        6. Stakeholders 

  • 2.  Research Methodology
    •   1 Research Data 
           1.1. Secondary Data
              1.1.1. Key Data from Secondary Sources
           1.2 Primary Data
              1.2.1. Key Data from Primary Sources
        3.Market Size Estimation 
        4. Market Breakdown and Data Triangulation 
        5. Assumptions for the Study 

  • 3.  Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights

  • 4.  Alpha 1 Lung Disease Market Variables, Trends & Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Application Overview
        6. Regulatory Framework
           6.1. Reimbursement Framework
           6.2. Standards and Compliances

  • 5.  Market Overview
    •   1. Market Dynamics
           1.1. Market Driver Analysis
              1.1.1. Increasing focus of Alpha 1 Lung Disease Market Companies on Brand Protection
              1.1.2. Untapped Opportunities in Emerging Regions
           1.2. Market Restraint Analysis
              1.2.1. High Cost Associated with Implementation of Predictive Analysis
           1.3. Industry Challenges
              1.3.1. Presence of Ambiguous Regulatory Framework

  • 6.  Alpha 1 Lung Disease Market Analysis Tools
    •   1. Industry Analysis - Porter’s
           1.1. Supplier Power
           1.2. Buyer Power
           1.3. Substitution Threat
           1.4. Threat from New Entrants
           1.5. Competitive Rivalry
        2. Pestel Analysis
           2.1. Political Landscape
           2.2. Environmental Landscape
           2.3. Social Landscape
           2.4. Application Landscape
           2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
           3.1. Joint Ventures
           3.2. Mergers and Acquisitions
           3.3. Licensing and Partnership
           3.4. Application Collaborations
           3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies

  • 7.  Alpha 1 Lung Disease Market, By Disease Type Historical Analysis and Forecast 2024-2032 (USD Million)
      1. Alpha-1 Antitrypsin Deficiency 
      2. Chronic Obstructive Pulmonary Disease (COPD)
      3. Pulmonary Fibrosis
      4. Bronchiectasis
      5. Others
         
  • 8.  Alpha 1 Lung Disease Market, By Treatment Type Historical Analysis and Forecast 2024-2032 (USD Million)
      1. Augmentation Therapy
      2. Bronchodilators
      3. Corticosteroids
      4. Oxygen Therapy
      5. Lung Transplantation
      6. Others
         
  • 9.  Alpha 1 Lung Disease Market, By Route of Administration Historical Analysis and Forecast 2024-2032 (USD Million)
      1. Inhalation
      2. Injectable
      3. Oral
         
  • 10.  Alpha 1 Lung Disease Market, By Distribution Channel Historical Analysis and Forecast 2024-2032 (USD Million)
      1. Hospital Pharmacies
      2. Retail Pharmacies
      3. Online Pharmacies
         
  • 11.  Alpha 1 Lung Disease Market, By End User Historical Analysis and Forecast 2024-2032 (USD Million)
      1. Hospitals
      2. Homecare
      3. Specialty Clinics
      4. Others
         
  • 12.  North America Alpha 1 Lung Disease Market Analysis 2018-2023 and Forecast 2024-2032 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2018-2023
           2.1. U.S.A
           2.2. Canada
           2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2024-2032

  • 13.  Latin America Alpha 1 Lung Disease Market Analysis 2018-2023 and Forecast 2024-2032 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2018-2023
           2.1. Brazil
           2.2. Venezuela
           2.3. Argentina
           2.4. Rest of Latin America
        3. Market Size (USD Million) Forecast for Latin America 2024-2032

  • 14.  Europe Alpha 1 Lung Disease Market Analysis 2018-2023 and Forecast 2024-2032 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2018-2023
           2.1. Germany
           2.2. U.K
           2.3. France
           2.4. Italy
           2.5. Spain
           2.6. Russia
           2.7. Poland
           2.8. Rest of Europe
        3. Market Size (USD Million) Forecast for Europe 2024-2032

  • 15.  Asia Pacific Alpha 1 Lung Disease Market Analysis 2018-2023 and Forecast 2024-2032 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2018-2023
           2.1. Japan
           2.2. China
           2.3. India
           2.4. Australia and New Zealand
           2.5. ASEAN
           2.6. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2024-2032 

  • 16.  Middle East and Africa Market Analysis 2018-2023 and Forecast 2024-2032 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2018-2023
           2.1. GCC
           2.2. Israel
           2.3. South Africa
           2.4. Rest of MEA
        3. Market Size (USD Million) Forecast for MEA 2024-2032

  • 17.  Market Share Analysis and Competitive Landscape
    •   1. Global Landscape - Key Players, Revenue and Presence
        2. Global Share Analysis - Key Players (Tier 1, Tier 2, Tier 3)
        3. Global Emerging Companies
        4. North America - Market Share Analysis and Key Regional Players
        5. Europe - Market Share Analysis and Key Regional Players
        6. Asia Pacific - Market Share Analysis and Key Regional Players
        7. Global Key Player - Growth Matrix

  • 18.  Company Profiles (Competition Dashboard, Competitors Deep Dive, Product Connected Devices and Disease Indication Portfolio, Financial Layouts)
    •   1. AstraZeneca
           1.1. Company Overview
           1.2. Product Portfolio
           1.3. SWOT Analysis
           1.4. Financial Overview
           1.5. Strategic Overview
        2. Boehringer Ingelheim
           2.1. Company Overview
           2.2. Product Portfolio
           2.3. SWOT Analysis
           2.4. Financial Overview
           2.5. Strategic Overview
        3. Roche
           3.1. Company Overview
           3.2. Product Portfolio
           3.3. SWOT Analysis
           3.4. Financial Overview
           3.5. Strategic Overview
        4. Novartis
           4.1. Company Overview
           4.2. Product Portfolio
           4.3. SWOT Analysis
           4.4. Financial Overview
           4.5. Strategic Overview
        5. Pfizer
           5.1. Company Overview
           5.2. Product Portfolio
           5.3. SWOT Analysis
           5.4. Financial Overview
           5.5. Strategic Overview
        6. Merck
           6.1. Company Overview
           6.2. Product Portfolio
           6.3. SWOT Analysis
           6.4. Financial Overview
           6.5. Strategic Overview
        7. Bristol-Myers Squibb
           7.1. Company Overview
           7.2. Product Portfolio
           7.3. SWOT Analysis
           7.4. Financial Overview
           7.5. Strategic Overview
        8. Takeda Pharmaceutical
           8.1. Company Overview
           8.2. Product Portfolio
           8.3. SWOT Analysis
           8.4. Financial Overview
           8.5. Strategic Overview
        9. CSL Behring 
           9.1. Company Overview
           9.2. Product Portfolio
           9.3. SWOT Analysis
           9.4. Financial Overview
           9.5. Strategic Overview
        10. Vertex Pharmaceuticals
           10.1. Company Overview
           10.2. Product Portfolio
           10.3. SWOT Analysis
           10.4. Financial Overview
           10.5. Strategic Overview
        11. Amgen
           11.1. Company Overview
           11.2. Product Portfolio
           11.3. SWOT Analysis
           11.4. Financial Overview
           11.5. Strategic Overview
        12. Sanofi
           12.1. Company Overview
           12.2. Product Portfolio
           12.3. SWOT Analysis
           12.4. Financial Overview
           12.5. Strategic Overview
        13. GlaxoSmithKline
           13.1. Company Overview
           13.2. Product Portfolio
           13.3. SWOT Analysis
           13.4. Financial Overview
           13.5. Strategic Overview
        14. Gilead Sciences
           14.1. Company Overview
           14.2. Product Portfolio
           14.3. SWOT Analysis
           14.4. Financial Overview
           14.5. Strategic Overview
        15. Eli Lilly
           15.1. Company Overview
           15.2. Product Portfolio
           15.3. SWOT Analysis
           15.4. Financial Overview
           15.5. Strategic Overview
        16. AbbVie
           16.1. Company Overview
           16.2. Product Portfolio
           16.3. SWOT Analysis
           16.4. Financial Overview
           16.5. Strategic Overview
        17. Johnson & Johnson
           17.1. Company Overview
           17.2. Product Portfolio
           17.3. SWOT Analysis
           17.4. Financial Overview
           17.5. Strategic Overview
        18. Teva Pharmaceutical 
           18.1. Company Overview
           18.2. Product Portfolio
           18.3. SWOT Analysis
           18.4. Financial Overview
           18.5. Strategic Overview
        19. Audentes Therapeutics
           19.1. Company Overview
           19.2. Product Portfolio
           19.3. SWOT Analysis
           19.4. Financial Overview
           19.5. Strategic Overview
        20. Regeneron Pharmaceuticals
           20.1. Company Overview
           20.2. Product Portfolio
           20.3. SWOT Analysis
           20.4. Financial Overview
           20.5. Strategic Overview

  • 19.  Pre and Post COVID-19 Impact
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the regulations initiated by healthcare administrations
        5. The overall economic slowdown of the developing and developed nations

  • 20.  FutureWise SME Key Takeaway Points for Client
    •   

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