Overview


According to FutureWise analysis, the market for Acute Hepatic Porphyria Treatment is expected to be US$ 0.01 billion in 2031 at a CAGR of 5.2% over the forecast period of 2023-2031.

Acute Hepatic Porphyria (AHP) is a group of rare genetic disorders characterized by the deficiency of specific enzymes involved in synthesizing heme, a crucial component of hemoglobin. The absence of these enzymes leads to the accumulation of certain intermediate compounds called porphyrins in the body, causing various symptoms. The objective of the treatment is to relieve the symptoms associated with acute attacks. Medications such as opioids or non-opioid analgesics can be administered to manage severe abdominal pain. For instance, Givosiran (Kineta®) is a first-of-its-kind RNAi therapy that has been shown to prevent acute attacks in patients with acute intermittent porphyria (AIP). It was approved by the EMA in 2022 and is currently under review by the US FDA.

Anti-nausea drugs may be prescribed to alleviate vomiting, and anti-anxiety medications can help control associated anxiety and agitation. Certain medications, hormones, and lifestyle factors can trigger acute attacks in individuals with AHP. It is essential to identify and avoid these triggers. Common triggers include certain medications (such as barbiturates, sulfonamide antibiotics, and hormonal medications), alcohol, fasting, hormonal changes (such as those occurring during menstruation or pregnancy), and stress. As AHP is a genetic disorder, individuals diagnosed with the condition may benefit from genetic counselling. Understanding the inheritance pattern can assist in evaluating the likelihood of passing on the disease to offspring and making informed decisions regarding family planning.

FutureWise Market Research has published a report that provides an insightful analysis of Acute Hepatic Porphyria Treatment Market trends that are affecting the overall market growth. This report will provide a detailed analysis of market share, regional insights, and competitor analysis that includes the stature of key manufacturers operational in this industry.

According to the analysis conducted by FutureWise research analysts, Acute Hepatic Porphyria Treatment Market is estimated to register a considerable growth rate over the forecast period. This report lists the market segments and potential prospects available across this industry, in addition to providing crucial information on the total valuation currently held by the industry. Moreover, this report will assist key management individuals in an organization to enhance their decisions pertaining to business expansion as well as strategic changes for increasing customer base. 

  • F. Hoffmann-La Roche Ltd.
  • Siemens
  • ACON Laboratories
  • Danaher
  • ARKRAY, Inc.
  • Abbott
  • Alnylam Pharmaceuticals, Inc
  • Boston Scientific Corporation
  • Bio-Rad Laboratories, Inc.
  • Pfizer Inc.
  • Teva Pharmaceutical Industries Ltd.
  • Mylan N.V.

(Note: The list of the major players will be updated with the latest market scenario and trends)

Improved understanding of AHP among healthcare professionals has increased awareness and better diagnosis rates. As a result, more patients are being identified and seeking appropriate treatment, thereby driving the demand for AHP therapies. AHP is classified as a rare disease, and many countries offer regulatory incentives, such as orphan drug designation, to encourage the development of therapies for rare conditions. These designations provide market exclusivity, tax benefits, and streamlined regulatory pathways, incentivizing pharmaceutical companies to invest in developing AHP treatments. Collaboration between pharmaceutical companies, academic institutions, and patient advocacy groups has been crucial in advancing AHP research and treatment development. These partnerships promote knowledge sharing, accelerate clinical trials, and facilitate the commercialization of new therapies, thereby driving market growth. A collaboration between AstraZeneca and Progenity to create and market PBGD mRNA, gene therapy for the treatment of AIP, was announced in 2022. AstraZeneca may be eligible to collect up to $500 million in upfront and milestone payments from the collaboration and royalties on any future PBGD mRNA sales. However, AHP is a rare disease, its symptoms are frequently vague and straightforward to confuse with those of other illnesses. Due to the possibility that healthcare providers may not first think of AHP as a potential cause, this can result in an underdiagnosis or a delayed diagnosis. Although hematin infusion is regarded as a routine treatment for acute attacks, few licensed treatments target AHP. Healthcare professionals and patients may have fewer options due to the absence of therapeutic choices, especially when hematin infusion may not be appropriate or successful thereby limiting the market growth.

By Type

  • Intermittent Porphyria (AIP)
  • Hereditary Coproporphyria (HCP)
  • Variegate Porphyria (VP)

By Treatment

  • Medications
  • Caloric Deprivation
  • Dehydration
  • Others

By Route of Administration

  • Oral
  • Parenteral
  • Others

By End User

  • Hospitals
  • Specialty
  • Clinics
  • Others

By Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Others

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

This market research report also emphasizes on factors affecting the growth rate in various regions listed above. A deep-down analysis of the region will also be provided in the final version of this market which is based on the conclusion of primary interviews and secondary data points gathered during the process.

By region, the market is segmented into North America, Latin America, Europe, Asia-Pacific, and Middle East & Africa. North America registered the highest share in the market in 2022. Several North American public and private health insurance firms have well-defined reimbursement policies for acute hepatic porphyria treatment. The prevalence of acute hepatic porphyria is higher in North America than in other regions. This is due to several factors, including genetic ancestry and environmental factors. The region also has a robust pharmaceutical industry that invests in research and development, leading to the availability of FDA-approved drugs and therapies for AHP treatment. This is leading to development of new and innovative treatments for the disease thereby contributing to the dominance in the AHP treatment market.

  • Tier 1 players- established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants

  • Growth prospects
  • SWOT analysis
  • Key trends
  • Key data-points affecting market growth

  • To provide with an exhaustive analysis on the Acute Hepatic Porphyria Treatment Market By Type, By Treatment, By Route Of Administration, By Distribution Channel, By End-user And By Region.
  • To cater comprehensive insights on factors such as drivers, restraints, trends, opportunity, and additionally segmental and regional factors impacting market growth.
  • To evaluate current market trends and forecast micro-markets and the overall market projections which are represented in the format of data-sets and ppt.
  • To predict the market size, in key regions— North America, Europe, Asia Pacific, Latin America and Middle East and Africa. 
  • To provide information on competitors which includes landscape mapping, technological advancements, R&D spending, news concerning strategic alliances, and new product launches.

  • We have a flexible delivery model and you can suggest changes in the scope/table of content as per your requirement
  • The customization Mobility Care offered are free of charge with purchase of any license of the report
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Table of Contents


  • 1.   Market Introduction
    •   1. Objectives of the Study
        2. Market Definition
        3. Market Scope
         3.1. Years Considered for the Study
         3.2. Market Covered
        4. Currency
        5. Limitations
        6. Stakeholders
  • 2.   Research Methodology
    •   1. Research Data
         1.1. Secondary Data
          1.1.1. Key Data from Secondary Sources
         1.2. Primary Data
          1.2.1. Key Data from Primary Sources
        2. Market Size Estimation
        3. Market Breakdown and Data Triangulation
        4. Assumptions for the Study
  • 3.   Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights
  • 4.   Acute Hepatic Porphyria Treatment Market Variables, Trends and Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Technology Overview
        6. Regulatory Framework
         6.1. Reimbursement Framework
         6.2. Standards and Compliances

  • 5.   Market Overview
    •   1. Market Dynamics
         1.1. Market Driver Analysis
          1.1.1. Increasing focus of Acute Hepatic Porphyria Treatment Market Companies on Brand Protection
          1.1.2. Untapped Opportunities in Emerging Regions
         1.2. Market Restraint Analysis
          1.2.1. High Cost Associated with Implementation of Predictive Analysis
         1.3. Industry Challenges
          1.3.1. Presence of Ambiguous Regulatory Framework
  • 6.   Acute Hepatic Porphyria Treatment Market Analysis Tools
    •   1. Industry Analysis - Porter’s
         1.1. Supplier Power
         1.2. Buyer Power
         1.3. Substitution Threat
         1.4. Threat from New Entrants
         1.5. Competitive Rivalry
        2. Pestel Analysis
         2.1. Political Landscape
         2.2. Environmental Landscape
         2.3. Social Landscape
         2.4. Technology Landscape
         2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
         3.1. Joint Ventures
         3.2. Mergers and Acquisitions
         3.3. Licensing and Partnership
         3.4. Technology Collaborations
         3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies
  • 7.   Acute Hepatic Porphyria Treatment Market, By Type Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Intermittent Porphyria (AIP)
        2. Hereditary Coproporphyria (HCP)
        3. Variegate Porphyria (VP)

  • 8.   Acute Hepatic Porphyria Treatment Market, By Treatment Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Medications
        2. Caloric Deprivation
        3. Dehydration
        4. Others

  • 9.   Acute Hepatic Porphyria Treatment Market, By Route of Administration Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Oral
        2. Parenteral
        3. Others

  • 10.   Acute Hepatic Porphyria Treatment Market, By End User Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Hospitals
        2. Specialty
        3. Clinics
        4. Others

  • 11.   Acute Hepatic Porphyria Treatment Market, By Distribution Channel Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Hospital Pharmacies
        2. Retail Pharmacies
        3. Others

  • 12.   North America Acute Hepatic Porphyria Treatment Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. U.S.A
         2.2. Canada
         2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2023-2031

  • 13.   Latin America Acute Hepatic Porphyria Treatment Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Brazil
         2.2. Venezuela
         2.3. Argentina
         2.4. Rest of Latin America
        3. Market Size (USD Million) Forecast for Latin America 2023-2031

  • 14.   Europe Acute Hepatic Porphyria Treatment Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Germany
         2.2. U.K
         2.3. France
         2.4. Italy
         2.5. Spain
         2.6. Russia
         2.7. Poland
         2.8. Rest of Europe
        3. Market Size (USD Million) Forecast for Europe 2023-2031

  • 15.   Asia Pacific Acute Hepatic Porphyria Treatment Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Japan
         2.2. China
         2.3. India
         2.4. Australia and New Zealand
         2.5. ASEAN
         2.6. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2023-2031

  • 16.   Middle East and Africa Acute Hepatic Porphyria Treatment Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. GCC
         2.2. Israel
         2.3. South Africa
         2.4. Rest of MEA
        3. Market Size (USD Million) Forecast for MEA 2023-2031

  • 17.   Market Share Analysis and Competitive Landscape
    •   1. Global Landscape - Key Players, Revenue and Presence
        2. Global Share Analysis - Key Players (Tier 1, Tier 2, Tier 3)
        3. Global Emerging Companies
        4. North America - Market Share Analysis and Key Regional Players
        5. Europe - Market Share Analysis and Key Regional Players
        6. Asia Pacific - Market Share Analysis and Key Regional Players
        7. Global Key Player - Growth Matrix
  • 18.   Company Profiles (Competition Dashboard, Competitors Deep Dive, Products Offered and Financial Layouts)
    •   1. F. Hoffmann-La Roche Ltd.
         1.1. Company Overview
         1.2. Product Portfolio
         1.3. SWOT Analysis
         1.4. Financial Overview
         1.5. Strategic Overview
        2. Siemens
         2.1. Company Overview
         2.2. Product Portfolio
         2.3. SWOT Analysis
         2.4. Financial Overview
         2.5. Strategic Overview
        3. ACON Laboratories
         3.1. Company Overview
         3.2. Product Portfolio
         3.3. SWOT Analysis
         3.4. Financial Overview
         3.5. Strategic Overview
        4. Danaher
         4.1. Company Overview
         4.2. Product Portfolio
         4.3. SWOT Analysis
         4.4. Financial Overview
         4.5. Strategic Overview
        5. ARKRAY, Inc.
         5.1. Company Overview
         5.2. Product Portfolio
         5.3. SWOT Analysis
         5.4. Financial Overview
         5.5. Strategic Overview
        6. Abbott
         6.1. Company Overview
         6.2. Product Portfolio
         6.3. SWOT Analysis
         6.4. Financial Overview
         6.5. Strategic Overview
        7. Alnylam Pharmaceuticals, Inc.
         7.1. Company Overview
         7.2. Product Portfolio
         7.3. SWOT Analysis
         7.4. Financial Overview
         7.5. Strategic Overview
        8. Boston Scientific Corporation
         8.1. Company Overview
         8.2. Product Portfolio
         8.3. SWOT Analysis
         8.4. Financial Overview
         8.5. Strategic Overview
        9. Bio-Rad Laboratories, Inc.
         9.1. Company Overview
         9.2. Product Portfolio
         9.3. SWOT Analysis
         9.4. Financial Overview
         9.5. Strategic Overview
        10. Pfizer Inc.
         10.1. Company Overview
         10.2. Product Portfolio
         10.3. SWOT Analysis
         10.4. Financial Overview
         10.5. Strategic Overview
        11. Teva Pharmaceutical Industries Ltd.
         11.1. Company Overview
         11.2. Product Portfolio
         11.3. SWOT Analysis
         11.4. Financial Overview
         11.5. Strategic Overview
        12. Mylan N.V.
         12.1. Company Overview
         12.2. Product Portfolio
         12.3. SWOT Analysis
         12.4. Financial Overview
         12.5. Strategic Overview

  • 19.   Pre and Post COVID-19 Impact
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the healthcare regulations initiated by administrations
        5. The overall economic slowdown of the developing and developed nations
  • 20.   FutureWise SME Key Takeaway Points for Client

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