According to FutureWise analysis, the market for Achondrogenesis is expected to grow at a CAGR of 4.32% over the forecast period of 2023-2031.
Achondrogenesis is a group of rare skeletal disorders that affects the development of cartilage and bones. These conditions are characterized by a small body, short limbs, and other skeletal anomalies. The conditions are life-threatening, and most affected infants are either stillborn or pass away shortly after birth due to respiratory failure. There are three types of achondrogenesis genetic conditions; type IA and type IB are autosomal recessive disorders, whereas achondrogenesis type II is an autosomal dominant disorder. All types of achondrogenesis are very severe skeletal dysplasias and are detected by prenatal ultrasound examination as early as week 14-17 of gestational age. Genetic mutations cause achondrogenesis, where each type of achondrogenesis is associated with a specific mutation. Mutations inherited from both parents induce Type 1A and 1B, whereas Type 2 results from new mutations arising at conception in infants with no prior family history of the disorder.
Achondrogenesis is categorized into three main types (1A, 1B, and 2), each with slightly different signs, symptoms, inheritance patterns, and genetic causes. Achondrogenesis type 1A, also known as the Houston-Harris type, is the least well-understood of the three types. Infants affected by this type have extremely short limbs, a narrow chest, easily fractured short ribs, and a deficiency in normal bone formation (ossification) in the skull, spine, and pelvis. Achondrogenesis type 1B, the Parenti-Fraccaro type, is characterized by exceptionally short limbs, a narrow chest, and a rounded abdomen. The fingers and toes tend to be short, and the feet may exhibit inward and upward (clubfeet). Also, affected infants frequently have a soft out-pouching around the belly button (an umbilical hernia) or near the groin (an inguinal hernia). Infants with achondrogenesis type 2, also referred to as the Langer-Saldino type, usually have brief arms and legs, a slender chest with short ribs, and underdeveloped lungs. This condition is also associated with a deficiency in the spine and pelvis ossification. Distinctive facial features like a small chin, a prominent forehead, and, in some, an opening in the top of the mouth (a cleft palate).
FutureWise Market Research has published a report that provides an insightful analysis achondrogenesis market trends that are affecting the overall market growth. This report will provide a detailed analysis of market share, regional insights, and competitor analysis that includes stature of key manufacturers operational in this industry.
According to the analysis conducted by FutureWise research analysts, achondrogenesis market is estimated to register a considerable growth rate over the forecast period. This report lists the market segments and potential prospects available across this industry, in addition providing crucial information on the total valuation currently held by the industry. Moreover, this report will assist key management individuals in an organisation to enhance their decisions pertaining to business expansion as well as strategic changes for increasing customer base.