Overview


According to FutureWise analysis, the market for ALAD Porphyria Treatment is expected to grow at a CAGR of 6.32% over the forecast period of 2023-2031.

ALAD porphyria is a rare genetic metabolic disease characterized by abnormally increased levels of porphyrins and their precursors in the body due to deficiencies of enzymes essential to synthesizing heme, a part of hemoglobin. There are various enzymes involved in heme synthesis in the liver and red blood cells. Delta-aminolevulinic acid dehydratase enzyme is also essential in heme production. It converts delta-aminolevulinic acid (ALA) to porphobilinogen (PBG). Symptoms vary from one individual to another but usually arise from the neurological and gastrointestinal systems. ALAD porphyria is inherited as an autosomal recessive disorder. Porphyrias are generally classified into two types: the “hepatic” and “erythropoietic. Excessive production of porphyrins and related substances mostly occurs in the liver for hepatic types, while in erythropoietic types, it predominantly stems from the bone marrow.

For a conclusive diagnosis of ADP, biochemical testing, which involves the identification of specific "biomarkers" in the blood or urine, is crucial. This includes the measurements of the biomarkers porphobilinogen (PBG), aminolevulinic acid, and total porphyrins in the urine should be done. Likewise, porphyrins in the blood should be measured. The body's PBG level can differ, so the best time for sample collection is during an acute attack (e.g., when an individual experiences abdominal pain). A mild increase in porphyrins is not diagnostic of ADP; the levels must be very high. The most accurate and sensitive method for confirming a specific Porphyria diagnosis is DNA testing, which identifies mutations in the Porphyria-causing gene.

FutureWise Market Research has published a report that provides an insightful ALAD porphyria treatment market trends that are affecting the overall market growth. This report will provide a detailed analysis of market share, regional insights, and competitor analysis that includes stature of key manufacturers operational in this industry.

According to the analysis conducted by FutureWise research analysts, ALAD porphyria treatment market is estimated to register a considerable growth rate over the forecast period. This report lists the market segments and potential prospects available across this industry, in addition providing crucial information on the total valuation currently held by the industry. Moreover, this report will assist key management individuals in an organisation to enhance their decisions pertaining to business expansion as well as strategic changes for increasing customer base.

  • Recordati Rare Diseases Inc.
  • Teva Pharmaceutical Industries Ltd.
  • Novartis AG
  • Pfizer Inc.
  • Johnson & Johnson
  • Mylan N.V.
  • AstraZeneca Plc.

(Note: The list of the major players will be updated with the latest market scenario and trends)

The increasing technological advancements in biotechnology, particularly in gene editing and delivery systems, hold immense promise for revolutionizing the treatment setting of ALAD porphyria. Techniques like CRISPR-Cas9 offer the potential to specifically target and repair the underlying genetic mutations responsible for the disorder, providing a definitive and long-lasting solution. Additionally, innovations in gene delivery mechanisms, such as viral vectors and nanoparticle-based systems, are enhancing the efficacy and specificity of delivering therapeutic genetic material and are expected to drive the growth of the ALAD porphyria treatment market over the forecast period. Moroever, the growing LAD porphyria attributed to orphan disease due to its extreme rarity acts as a crucial driver in pharmaceutical companies to invest in research and development for treatments. This identification grants exclusive market rights for a specified period, offering a safeguard against competition, which might be particularly pivotal for recouping substantial R&D investments. Additionally, pharmaceutical companies receive tax credits and incentives, creating a more favorable economic environment for developing therapies targeting this niche market. Therefore, the rising incidence of rare disorders is anticipated to propel the market growth. However, as an exceptionally rare condition, ALAD Porphyria presents a significant barrier in various aspects of its management. The lack of cases limits the research available, resulting in a shortage of clinical expertise and tailored treatment options. This rarity also hampers its recognition among healthcare professionals, potentially leading to delayed or missed diagnoses. This critical delay may lead to prolonged suffering for individuals, as timely intervention is vital in relieving the severity of symptoms and preventing acute attacks. Additionally, the lack of cases may also impede the development of specialized care centers and targeted therapies, further worsening the difficulties faced by individuals affected by this condition. Therefore, hindering the market growth over the projection period.

By Drug Type

  • NSAIDS
  • Anti-Emetics
  • Enzyme Inhibitors
  • Others

By Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies/Drugstores
  • E-Commerce

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

This market research report also emphasis on factors affecting the growth rate in various regions listed above. A deep-down analysis of region will also be provided in the final version of this market which is based on conclusion of primary interviews and secondary data point gathered during the process.

By region, the market is segmented into North America, Latin America, Europe, Asia-Pacific, and Middle East & Africa. North America registered highest share in the market in 2022. Due to the increasing prevalence of diseases, growing awareness among major stakeholders due to high penetration, presence of major key players, rise in healthcare expenditure, FDA approvals for the products, and increasing government efforts for spreading awareness about the disease in the U.S. will expand the ALAD porphyria treatment market. For instance, according to the American Porphyria Foundation, Porphyria Awareness Week takes place from April 2 to April 9, 2022. During this period, patients are invited to raise awareness in their local communities while participating in community-building initiatives for patient-driven awareness and fundraising efforts. The APF will offer educational resources to physicians, healthcare professionals, and the public to support patient-led initiatives for awareness and fundraising. Additionally, rising R&D activities and development in clinical trials will provide beneficial opportunities, further driving the market growth during the projection in the region.

  • Tier 1 players- established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants

  • Growth prospects
  • SWOT analysis
  • Key trends
  • Key data-points affecting market growth

  • To provide with an exhaustive analysis on the ALAD Porphyria Treatment Market By Drug Type, By Distribution Channel and By Region.
  • To cater comprehensive insights on factors such as drivers, restraints, trends, opportunity, and additionally segmental and regional factors impacting market growth.
  • To evaluate current market trends and forecast micro-markets and the overall market projections which are represented in the format of data-sets and ppt.
  • To predict the market size, in key regions— North America, Europe, Asia Pacific, Latin America and Middle East and Africa. 
  • To provide information on competitors which includes landscape mapping, technological advancements, R&D spending, news concerning strategic alliances, and new product launches

  • We have a flexible delivery model and you can suggest changes in the scope/table of content as per your requirement
  • The customization Mobility Care offered are free of charge with purchase of any license of the report
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Table of Contents


  • 1.   Market Introduction
    •   1. Objectives of the Study
        2. Market Definition
        3. Market Scope
         3.1. Years Considered for the Study
         3.2. Market Covered
        4. Currency
        5. Limitations
        6. Stakeholders
  • 2.   Research Methodology
    •   1. Research Data
         1.1. Secondary Data
          1.1.1. Key Data from Secondary Sources
         1.2. Primary Data
          1.2.1. Key Data from Primary Sources
        2. Market Size Estimation
        3. Market Breakdown and Data Triangulation
        4. Assumptions for the Study
  • 3.   Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights
  • 4.   ALAD Porphyria Treatment Market Variables, Trends and Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Type Overview
        6. Regulatory Framework
         6.1. Reimbursement Framework
         6.2. Standards and Compliances

  • 5.   Market Overview
    •   1. Market Dynamics
         1.1. Market Driver Analysis
          1.1.1. Increasing focus of ALAD Porphyria Treatment Market Companies on Brand Protection
          1.1.2. Untapped Opportunities in Emerging Regions
         1.2. Market Restraint Analysis
          1.2.1. High Cost Associated with Implementation of Predictive Analysis
         1.3. Industry Challenges
          1.3.1. Presence of Ambiguous Regulatory Framework
  • 6.   ALAD Porphyria Treatment Market Analysis Tools
    •   1. Industry Analysis - Porter’s
         1.1. Supplier Power
         1.2. Buyer Power
         1.3. Substitution Threat
         1.4. Threat from New Entrants
         1.5. Competitive Rivalry
        2. Pestel Analysis
         2.1. Political Landscape
         2.2. Environmental Landscape
         2.3. Social Landscape
         2.4. Type Landscape
         2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
         3.1. Joint Ventures
         3.2. Mergers and Acquisitions
         3.3. Licensing and Partnership
         3.4. Type Collaborations
         3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies
  • 7.   ALAD Porphyria Treatment Market, By Drug Type Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. NSAIDS
        2. Anti-Emetics
        3. Enzyme Inhibitors
        4. Others

  • 8.   ALAD Porphyria Treatment Market, By Distribution Channel Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Hospital Pharmacies
        2. Retail Pharmacies/Drugstores
        3. E-Commerce

  • 9.   North America ALAD Porphyria Treatment Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. U.S.A
         2.2. Canada
         2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2023-2031

  • 10.   Latin America ALAD Porphyria Treatment Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Brazil
         2.2. Venezuela
         2.3. Argentina
         2.4. Rest of Latin America
        3. Market Size (USD Million) Forecast for Latin America 2023-2031

  • 11.   Europe ALAD Porphyria Treatment Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Germany
         2.2. U.K
         2.3. France
         2.4. Italy
         2.5. Spain
         2.6. Russia
         2.7. Poland
         2.8. Rest of Europe
        3. Market Size (USD Million) Forecast for Europe 2023-2031

  • 12.   Asia Pacific ALAD Porphyria Treatment Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Japan
         2.2. China
         2.3. India
         2.4. Australia and New Zealand
         2.5. ASEAN
         2.6. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2023-2031

  • 13.   Middle East and Africa ALAD Porphyria Treatment Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. GCC
         2.2. Israel
         2.3. South Africa
         2.4. Rest of MEA
        3. Market Size (USD Million) Forecast for MEA 2023-2031

  • 14.   Market Share Analysis and Competitive Landscape
    •   1. Global Landscape - Key Players, Revenue and Presence
        2. Global Share Analysis - Key Players (Tier 1, Tier 2, Tier 3)
        3. Global Emerging Companies
        4. North America - Market Share Analysis and Key Regional Players
        5. Europe - Market Share Analysis and Key Regional Players
        6. Asia Pacific - Market Share Analysis and Key Regional Players
        7. Global Key Player - Growth Matrix
  • 15.   Company Profiles (Competition Dashboard, Competitors Deep Dive, Products Offered and Financial Layouts)
    •   1. Recordati Rare Diseases Inc.
         1.1. Company Overview
         1.2. Product Portfolio
         1.3. SWOT Analysis
         1.4. Financial Overview
         1.5. Strategic Overview
        2. Teva Pharmaceutical Industries Ltd.
         2.1. Company Overview
         2.2. Product Portfolio
         2.3. SWOT Analysis
         2.4. Financial Overview
         2.5. Strategic Overview
        3. Novartis AG
         3.1. Company Overview
         3.2. Product Portfolio
         3.3. SWOT Analysis
         3.4. Financial Overview
         3.5. Strategic Overview
        4. Pfizer Inc.
         4.1. Company Overview
         4.2. Product Portfolio
         4.3. SWOT Analysis
         4.4. Financial Overview
         4.5. Strategic Overview
        5. Johnson & Johnson
         5.1. Company Overview
         5.2. Product Portfolio
         5.3. SWOT Analysis
         5.4. Financial Overview
         5.5. Strategic Overview
        6. Mylan N.V.
         6.1. Company Overview
         6.2. Product Portfolio
         6.3. SWOT Analysis
         6.4. Financial Overview
         6.5. Strategic Overview
        7. AstraZeneca Plc.
         7.1. Company Overview
         7.2. Product Portfolio
         7.3. SWOT Analysis
         7.4. Financial Overview
         7.5. Strategic Overview

  • 16.   Pre and Post COVID-19 Impact
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the healthcare regulations initiated by administrations
        5. The overall economic slowdown of the developing and developed nations
  • 17.   FutureWise SME Key Takeaway Points for Client

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